首页> 外文会议>2010 4th International Conference on Bioinformatics and Biomedical Engineering >Effects of Aluminum Exposure on Antioxidative Activity and Humoral Immune Function in Chickens: Preliminary Study of Aluminum Accumulation on Immune System in Chickens
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Effects of Aluminum Exposure on Antioxidative Activity and Humoral Immune Function in Chickens: Preliminary Study of Aluminum Accumulation on Immune System in Chickens

机译:铝暴露对鸡抗氧化活性和体液免疫功能的影响:铝积累对鸡免疫系统的初步研究

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The activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and concentrations of malondialdehyde (MAD) in serum, spleen and bursa of Fabricius and the concentrations of Immunoglobulin G (IgG),Immunoglobulin A (IgA) , Immunoglobulin M (IgM) and HI antibody titer to Newcastle Disease in serum were detected in chickens with different levels sub-chronic aluminum (Al) intoxication produced by continuous peritoneal injection of various gradient aluminum trichloride (AlCl3). The results showed that the concentrations of MDA in chickens were higher and other indexes were lower in the experimental groups than in the control group. There was significantly different (P<0.05 or P<0.01) between groups, dose-effect relationship between with AlCl3. The results indicate that Al exposure inhibits the antioxidative activity and humoral immune function in chickens.
机译:血清,脾脏和法氏囊中超氧化物歧化酶(SOD),谷胱甘肽过氧化物酶(GSH-Px)的活性和丙二醛(MAD)的浓度以及免疫球蛋白G(IgG),免疫球蛋白A(IgA),免疫球蛋白M(在连续腹膜注射各种梯度三氯化铝(AlCl3)产生不同水平的亚慢性铝(Al)中毒的鸡中,检测到血清中新城疫的IgM和HI抗体滴度。结果表明,实验组的鸡MDA浓度高于对照组,其他指标均低于对照组。各组之间存在显着性差异(P <0.05或P <0.01),与AlCl3之间的剂量-效应关系。结果表明,铝暴露抑制了鸡的抗氧化活性和体液免疫功能。

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