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首页> 外文会议>World Automation Congress >Junkai Li, Hui Wan, Haisheng Lv, Guofeng Guan* College of Chemistry and Chemical Engineering Nanjing University of Technology Nanjing 210009, PR China E-mail:guangf@njut. edu. cn
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Junkai Li, Hui Wan, Haisheng Lv, Guofeng Guan* College of Chemistry and Chemical Engineering Nanjing University of Technology Nanjing 210009, PR China E-mail:guangf@njut. edu. cn

机译：Junkai Li, Hui Wan, Haisheng Lv, Guofeng Guan* College of Chemistry and Chemical Engineering Nanjing University of Technology Nanjing 210009, PR China E-mail:guangf@njut. edu. cn

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To examine the toxicity of residue of succinylcholine chloride (SCC), the residue of SCC from experimental mice killed by 2ml 10 g/L injection of SCC was determined by the method of H-NMR and the residue toxicity was tested. 60 mice divided into six groups, were given with SCC, 625, 62.5, 6.25, 0.625 mg/kg, administered orally by the dose of 50mg; The control group were fed with the same amount dose with distilled water; cyclophosphamide toxicity tests for the same amount of control group; Accumulation coefficient method was used to examine the coefficient using 40 mice. Results showed that the content of drug residue of SCC is about 4mg in an experimental mouse. A cute toxicity test showed the LD50 is about 79mg/kg, accumulation coefficient (k) is 0.67， less than 1.
机译：为了检查琥珀酰氯（SCC）残余物的毒性，通过H-NMR的方法测定由2mL 10g / L的实验小鼠杀死的实验小鼠的SCC残基，并测试残留物毒性。将60只小鼠分成6组，给予SCC，625,62.5,6.25,0.625mg / kg，口服给药剂量为50mg;用蒸馏水用相同量的剂量加入对照组;环磷酰胺毒性试验相同量的对照组;累积系数法用于使用40只小鼠检查系数。结果表明，在实验小鼠中，SCC的药物残留物的含量约为4mg。可爱的毒性测试显示LD50约为79mg / kg，累积系数（k）为0.67，小于1。

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