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A reaction-diffusion model of the human brain development

机译:人脑发育的反应扩散模型

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The anatomical variability of the human brain folds remains an unclear and challenging issue. Several hypotheses coexist for explaining the rapid development of cortical sulci and it is clear that understanding their variability would improve the comparison of anatomical and functional data across cohorts of subjects. In this article we propose to extend a model of cortical folding based on reaction-diffusion mechanisms. The originality of our approach lies in the fact that the surface on which these mechanisms take place is deformed iteratively and engenders geometric patterns that can be linked to cortical sulci. We show that some statistic properties of our model can reflect the variability of sulcal structures.
机译:人脑折叠的解剖学变异性仍然是不清楚和具有挑战性的问题。几个假说共存以解释皮质沟的快速发展,并且很显然,了解它们的变异性将改善不同人群的解剖学和功能数据的比较。在本文中,我们建议扩展基于反应扩散机制的皮质折叠模型。我们的方法的独创性在于,发生这些机制的表面会反复变形,并产生可与皮质沟相连的几何图案。我们表明,我们模型的某些统计特性可以反映出沟渠结构的变异性。

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