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Influence of Soft Tissues on Ultrasonic Lamb Waves in Synthesised Soft Tissue-Bone Phantoms

机译:软组织对合成的软组织骨模型中超声波兰姆波的影响

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Majority of existing quantitative ultrasound (QUS) techniques in today's clinic examine the first-arriving-signal (FAS) to assess bone properties for the ease in identifying FAS in captured time domain signals. However, FAS can fail to access fine details of bone including those relevant to osteoporotic properties, as a result of its large wavelength. Awareness of this weakness has led to increasing preferences to use other wave modes subsequent to FAS in ultrasound signals by taking advantage of their shorter wavelengths. Of particular interests are transverse waves. Transverse wave modes have been demonstrated capable of offering precision-enhanced assessment of bone properties. Nevertheless soft tissues coupled with bone can exert remarkable influence on these wave modes propagating in bone, lowering assessment accuracy without appropriate rectification. Such a coupling effect is largely ignored in clinical QUS. Characteristics of various ultrasonic wave modes in synthesised soft tissue-bone phantoms (fabricated using bone- and soft tissue-mimic materials) were interrogated using a three-dimensional finite element simulation technique and an in vitro testing approach. Effect of thickness and elastic property of overlying soft tissues on ultrasonic waves was examined and calibrated quantitatively. Results have shown that appropriate compensation for the medium coupling effect on ultrasonic waves is of vital necessity when developing high-precision QUS techniques for clinical bone assessment.
机译:当今诊所中,大多数现有的定量超声(QUS)技术都会检查首次到达信号(FAS)来评估骨骼属性,以便于在捕获的时域信号中轻松识别FAS。然而,由于其波长长,FAS可能无法访问骨骼的精细细节,包括与骨质疏松性质有关的细节。意识到这种弱点后,通过利用短波优势,人们越来越倾向于在超声信号中使用FAS之后的其他波模式。特别令人感兴趣的是横波。横向波模式已被证明能够提供对骨骼特性的精确增强评估。但是,软组织与骨骼耦合会对这些在骨骼中传播的波模产生显着影响,从而在没有适当矫正的情况下降低了评估准确性。这种耦合效应在临床QUS中被忽略了。使用三维有限元模拟技术和体外测试方法,对合成的软组织-骨模型(使用骨和软组织-模拟材料制造)中各种超声波模式的特性进行了研究。检查了覆盖的软组织的厚度和弹性特性对超声波的影响,并进行了定量校准。结果表明,在开发用于临床骨评估的高精度QUS技术时,至关重要的是必须适当补偿对超声波的介质耦合效应。

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