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Comparison Between Continuous and Discrete Absorption Weighting for Monte Carlo Modeling Photon Transport in Tissue

机译:蒙特卡罗模拟组织中光子传输的连续和离散吸收权重的比较

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Monte Carlo method was frequently used to provide flexible and rigorous estimates of photon migration in turbid media in the field of biomedical optics. Most researchers prefer discrete (DAW) to continuous absorption weighting (CAW), but few quantitative comparisons have been provided. We picked out the widely used Monte Carlo software MCML which was also based on DAW, and developed it to CAW-based MCML. By using typical biological tissue layer with multiple depth, we computed light transport properties with the above two method and compared them on time consumption and precision. Finally, we found that CAW showed more than twice precision than DAW in depth< 1 mm tissue and took less than 5% extral time consumption. Thus, DAW is recommend to use in analyzing light transport in depth< 1 mm biological sample in optical microscopy.
机译:在生物医学光学领域中,经常使用蒙特卡洛方法来提供灵活,严格的浊度介质中光子迁移的估计。大多数研究人员更喜欢离散(DAW)而不是连续吸收加权(CAW),但几乎没有提供定量比较。我们挑选了同样基于DAW的广泛使用的蒙特卡洛软件MCML,并将其开发为基于CAW的MCML。通过使用具有多个深度的典型生物组织层,我们使用上述两种方法计算了光传输特性,并比较了它们的时间消耗和精度。最终,我们发现,在<1 mm的组织深度上,CAW的精度是DAW的两倍以上,并且节省了不到5%的额外时间。因此,建议在光学显微镜中使用DAW分析深度小于1 mm的生物样品中的光传输。

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