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A new 3D-tomographic ultrasound imaging concept for breast cancer and rheumatoid arthritis diagnostics avoiding water bath techniques

机译:避免水浴技术的乳腺癌和类风湿关节炎诊断的新3D断层超声成像概念

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Superposition of pulse-echo data (FASC: Full Angle Spatial Compounding) acquired from 360° around an object in a water bath as imaging concept for an Ultrasound Computed Tomography (USCT) add-on system has already shown a great potential in 2D for in-vivo investigations (e.g. breast cancer imaging). However, providing a small number of images for parallel cross-sectional planes with enhanced image quality is not sufficient for diagnostics. Volume datasets (3D) are needed. For this purpose we further developed our USCT add-on system to automatically rotate a motorized array (3D probe) around the object of investigation. Full integration of external motor and ultrasound electronics control in a custom made program allows acquiring 3D radio-frequency (rf) datasets from 360° within an appropriate data acquisition time for in-vivo investigations. With respect to breast cancer imaging this concept also enables imaging of thorax close tissue regions which cannot be achieved by 2D FASC. Furthermore, moldings of polyvinyl alcohol (PVA) hydrogel adapted to respective body parts (e.g. female breast) have been developed as new concept for coupling. These PVA hydrogel moldings have a great potential to replace water bath technique in USCT. The water bath technique is in general assumed to be critical for clinical environments. In this contribution we present FASC volume datasets of a tissue mimicking breast phantom investigated in a water bath as well as with PVA hydrogel moldings used for coupling. Results show a great potential for 3D FASC with a motorized array (3D probe) and for the coupling concept with PVA hydrogel moldings.
机译:脉冲回声数据(FASC:全角度空间复合)从水浴中的物体周围获得的360°作为超声计算断层扫描(USCT)附加系统的成像概念已经显示出在2D中的巨大潜力-Vivo调查(例如乳腺癌成像)。然而,为具有增强的图像质量的平行横截面平面提供少量图像,不足以诊断。需要卷数据集(3D)。为此,我们进一步开发了USCT附加系统,以在调查对象周围自动旋转电动阵列(3D探针)。外部电机和超声电子控制在定制程序中的完全集成允许在适当的数据采集时间内从360°获取3D射频(RF)数据集以进行体内调查。对于乳腺癌成像,这一概念还使得能够通过2D FASC实现无法实现的胸部关闭组织区域。此外,已经开发了适用于各自的身体部位(例如雌性乳房)的聚乙烯醇(PVA)水凝胶的成型作为耦合的新概念。这些PVA水凝胶模塑具有巨大的潜力,可以在USCT中取代水浴技术。水浴技术通常是对临床环境至关重要。在这一贡献中,我们呈现了在水浴中研究的乳房幻影的组织的Fasc体积数据集以及用于偶联的PVA水凝胶模制品。结果对带电动阵列(3D探针)的3D FASC具有很大的潜力,以及具有PVA水凝胶成型的耦合概念。

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