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Effect of Left-Right Heart During Biventricular Assist Device Support by Speed Synchronization: A Computer Study

机译:左心在双心辅助装置支撑期间的速度同步效果:计算机研究

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Biventricular assist device(BiVAD)is a treatment for the end-stage heart failure patients.Normally,after left ventricular assist device(LVAD)implanted in the end-stage heart failure patients,a right heart failure immediately appeared.Then,the right ventricular assist device(LVAD)was implanted.Both LVAD and RVAD implanted so call BiVAD.Additionally,the speed synchronization is a novel concept for remaining the high preload and increasing the cardiac output.It is a potential to promote a bridge to recovery treatment.The cardiovascular,RVAD,LVAD and speed synchronization models(co-pulse mode)are implemented using MATLAB.The normal heart and pathology heart are used in this study.The pathology level of the heart was regulated by a level of maximum elastance(Emax: 30% of normal heart value)in the heart model.The constant speed mode and co-pulse mode(increasing pump speed in systolic period between 8,000-11,000 rpm)are simulated using the MicroMed-DeBakey VAD model.The hemodynamics,ejection fraction,pressure-volume loop and pressure volume area(PVA)of different heart condition and pump mode are simulated.The results indicated the aortic pressure,pulmonary artery pressure and ejection fraction in co-pulse mode are similar to the constant speed mode.However,PVA in co-pulse mode are higher than the constant speed mode on pathology heart.In conclusion,mis computer simulation can re-generated the effect of BiVAD under the pathological condition.The optimal ratio of RVAD support is important to prevent the suction event.Speed synchronization can maintain the high PVA than constant speed.Therefore,partial support with co-pulse mode can potentially use for the bridge to recovery treatment.
机译:五年级辅助装置(双层)是终级心力衰竭患者的治疗方法。在植入末期心力衰竭患者中植入左心室辅助装置(LVAD)后,立即出现右心力衰竭。然后,右心室辅助设备(LVAD)被植入。植入LVAD和RVAD植入所以呼叫Bivad.Aditionally,速度同步是一种新颖的概念,用于剩下高预紧和增加心输出。它是促进恢复桥梁的潜力。使用Matlab实现心血管,RVAD,LVAD和速度同步模型(共脉冲模式)。本研究中使用正常的心脏和病理心脏。心脏的病理水平受到最大弹性水平的调节(Emax:30心脏模型中的常规心价的百分比。使用Micromed-DeBakey Vad模型模拟恒定速度模式和共脉冲模式(增加8,000-11,000 rpm之间的泵速度)。血流动力学,喷射模拟不同心脏状况和泵模式的级分,压力体积回路和压力体积面积(PVA)。结果表明了共脉冲模式中的主动脉压力,肺动脉压和喷射部分类似于恒定速度模式。但是,PVA在共脉冲模式下高于病理心脏的恒定速度模式。结论,MIS计算机仿真可以在病态条件下重新产生双边饼的效果。RVAD支持的最佳比率对于防止抽吸事件非常重要。 .ED同步可以保持高PVA而不是恒定速度。因此,具有共脉冲模式的部分支撑可能用于桥接恢复处理。

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