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首页> 外文会议>Conference on image-guided procedures, robotic interventions, and modeling >Towards Enabling Ultrasound Guidance in Cervical Cancer High-Dose-Rate Brachytherapy
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Towards Enabling Ultrasound Guidance in Cervical Cancer High-Dose-Rate Brachytherapy

机译：寻求在宫颈癌大剂量率近距离放射治疗中启用超声引导

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MRI and Computed Tomography (CT) are used in image-based solutions for guiding High Dose Rate (HDR) brachytherapy treatment of cervical cancer. MRI is costly and CT exposes the patients to ionizing radiation. Ultrasound, on the other hand, is affordable and safe. The long-term goal of our work is to enable the use of multiparametric ultrasound imaging in image-guided HDR for cervical cancer. In this paper, we report the development of enabling technology for ultrasound guidance and tissue typing. We report a system to obtain the 3D freehand transabdominal ultrasound RF signals and B-mode images of the uterus, and a method for registration of ultrasound to MRI. MRI and 3D ultrasound images of the female pelvis were registered by contouring the uterus in the two modalities, creating a surface model, followed by rigid and B-spline deformable registration. The resulting transformation was used to map the location of the tumor from the T2-weighted MRI to ultrasound images and to determine cancerous and normal areas in ultrasound. B-mode images show a contrast for cancer vs. normal tissue. Our study shows the potential and the challenges of ultrasound imaging in guiding cervical cancer treatments.
机译：MRI和计算机断层扫描（CT）用于基于图像的解决方案，以指导高剂量率（HDR）近距离治疗宫颈癌。 MRI成本高昂，而CT将患者暴露在电离辐射下。另一方面，超声波既经济又安全。我们工作的长期目标是能够在宫颈癌的图像引导HDR中使用多参数超声成像。在本文中，我们报告了超声引导和组织分型的支持技术的发展。我们报告了一个系统，以获得子宫的3D徒手经腹超声RF信号和B型图像，以及一种向MRI进行超声注册的方法。通过以两种方式勾勒子宫轮廓，记录女性骨盆的MRI和3D超声图像，创建表面模型，然后进行刚性和B样条可变形对齐。所得的变换用于将肿瘤的位置从T2加权MRI映射到超声图像，并确定超声中的癌变区域和正常区域。 B模式图像显示出癌症与正常组织的对比。我们的研究表明了超声成像在指导宫颈癌治疗中的潜力和挑战。

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