Predicting Clinical Status of Patients After an Acute Ischemic Stroke Using Random Forests

机译：使用随机林预测急性缺血性脑卒中患者的临床状态

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According to the World Health Organization, a stroke has been the second most common cause of death in the world in the last 15 years. An ischemic stroke accounts for almost 80% of all cases. The University Hospital Ostrava in the Czech Republic collects various information about patients who were transported there after suffering from an acute ischemic stroke, such as the affected brain hemisphere, duration of medical procedure or presence of hypertension. The objective of this paper was finding a model which would be able to predict patient's clinical outcome three months after an ischemic stroke based on the collected data. It was also desirable to analyse importance of the considered variables. For this purpose, the random forests algorithm was used. To avoid biased variable importance, we used an alternative approach to the random forests which uses the conditional inference trees. Firstly, the commonly used modified Rankin Scale was used for describing the patient's outcome three months after a stroke. Secondly, only two values for the clinical status were considered, by meaning they correspond with the values 0-3 and 4-6 of modified Rankin Scale. The best performance was achieved with the second approach to description of the clinical outcome with the calculated classification accuracy 86%.

机译：根据世界卫生组织的说法，在过去的15年里，中风是世界上世界上最常见的死亡原因。缺血性卒中占所有病例的近80％。捷克共和国大学医院奥斯特拉虎收集有关在患有急性缺血性卒中后在那里进行的各种信息，例如受影响的脑半球，医疗程序的持续时间或高血压的存在。本文的目的是找到一种模型，该模型将能够在基于所收集的数据的缺血性卒中后三个月预测患者的临床结果。还希望分析所考虑的变量的重要性。为此，使用随机林算法。为避免偏见的变量重要性，我们使用了一种使用条件推理树的随机林的替代方法。首先，常用的改进的rankin规模用于描述中风三个月后的患者的结果。其次，考虑了临床状态的两个值，其含义与改进的Rankin规模的值0-3和4-6相对应。通过计算分类精度的临床结果描述的第二种方法实现了最佳性能。

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《International Conference on Information and Digital Technologies》|2017年|458p|共6页
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Adela Vrtkova;
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1. Endovascular therapy is effective and safe for patients with severe ischemic stroke: pooled analysis of Interventional Management of Stroke III and Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands Data (vol 46, pg 3416, 2015) [J] . Broderick J. P., Berkhemer O. A., Paleseh Y. Y., Stroke: A Journal of Cerebral Circulation . 2016,第1期

机译：血管内疗法对重度缺血性中风患者有效且安全：荷兰数据（第46卷，第3416页，2015年）汇总的中风III介入治疗和多中心随机临床试验对急性缺血性中风的综合分析
2. EFFECT OF SIMVASTATIN ON THE PROGNOSIS AND THE CHANGES OF THE CLINICAL STATUS IN PATIENTS WITH ACUTE ISCHEMIC STROKE. THE RESULTS OF THE 12 MONTH RANDOMIZED, OPEN COMPARATIVE STUDY [J] . V. V. Yakusevich, A. Yu. Malygin, A. V. Kabanov Racional?naa Farmakoterapia v Kardiologii . 2013,第4期

机译：辛伐他汀对急性缺血性卒中患者的预后及临床状况的影响12个月随机开放比较研究的结果
3. Clinical predictors of death in young and middle-aged patients with ischemic stroke or transient ischemic attack: long-term results of the Vienna Stroke Registry : Clinical predictors of ischemic stroke mortality in patients <60 years. [J] . Greisenegger S, Zehetmayer S, Ferrari J, Journal of neurology . 2011,第6期

机译：缺血性中风或短暂性脑缺血发作的年轻和中年患者死亡的临床预测指标：Vienna Stroke Registry的长期结果：<60岁患者中缺血性中风死亡率的临床预测指标。
4. Predicting Clinical Status of Patients After an Acute Ischemic Stroke Using Random Forests [C] . Adela Vrtkova International Conference on Information and Digital Technologies . 2017

机译：使用随机林预测急性缺血性脑卒中患者的临床状态
5. Assessment of health-related quality-of-life outcomes in patients diagnosed with acute ischemic stroke. [D] . Karukin, Michael. 1997

机译：评估诊断为急性缺血性中风的患者与健康相关的生活质量结局。
6. Machine Learning-Based Prediction of Brain Tissue Infarction in Patients With Acute Ischemic Stroke Treated With Theophylline as an Add-On to Thrombolytic Therapy: A Randomized Clinical Trial Subgroup Analysis [O] . Boris Modrau, Anthony Winder, Niels Hjort, 2021

机译：用茶碱治疗急性缺血性卒中患者脑组织梗死的机器学习预测作为溶栓治疗：随机临床试验亚组分析
7. MODERATED EPOSTERS1385Longitudinal strain assessment in dilated cardiomyopathy patients using a novel accelerated DENSE sequence1407Simultaneous T1 and T2 cardiac quantification with CABIRIA: initial clinical experience1423Head-to-head comparison of acceleration algorithms in 4-dimensional flow CMR1502Left ventricular function and size evaluated by hybrid cardiac positron emission tomography-magnetic resonance: Intraindividual comparison of left ventricular ejection fraction and ventricular volumes derived by two modalities1510Left Atrium assessed by Cardiovascular Magnetic Resonance at 1.5 and 3 Tesla – age and gender effects1514Comparison of Free Breathing Cardiac MRI Radial technique to the Standard Multi breath-hold cine SSFP CMR technique for the assessment of LV Volumes and Function1536Self-navigated free-breathing isotropic 3D whole heart phase sensitive inversion recovery magnetic resonance without navigator for detection of myocardial infarction1547Assessment of Right Ventricular Strain Using Myocardial Deformation Recovery Semi Automated Technique: Initial Experience and Normal Values1586Tissue tracking myocardial deformation analysis and prediction of left ventricular remodeling in acute myocardial infarction1589Investigating strategies for optimal 31P MRS clinical cardiac at 3T: Initial Results1620Quantitative Criteria for the Diagnosis of the Congenital Absence of Pericardium by Cardiac Magnetic Resonance1632Widespread tissue injury during acute myocardial infarction: evidence from advanced CMR relaxometry1322Computed tomography coronary angiography verSus sTRess cArdiac magneTic rEsonance for the manaGement of sYmptomatic revascularized patients: a cost effectiveness study (STRATEGY study)1339Comparison of low- versus high-dose of gadobutrol for late gadolinium enhancement imaging at 1.5 Tesla: a clinical feasibility study1347Multi-parametric Cardiac Magnetic Resonance for Prediction of Cardiac Complications in Thalassemia Intermedia: a Prospective Multicenter Study1461Prognostic value of Cardiovascular Magnetic Resonance derived indexes of myocardial fibrosis in heart transplant recipients1523The role of CMR in the acute phase of hospitalization: changing paradigms1542Preoperative CMR-based score predict ventricular response after surgical left ventricular reconstruction in ischemic heart failure patients1555Excellent response rate to cardiac resynchronization therapy guided with magnetic resonance imaging1626The ECG as a predictor of arrhythmogenic substrate on Cardiac Magnetic Resonance Imaging in patients undergoing ablation for premature ventricular contractions1649Comparison of T1-mapping at 3.0T CMR and angiographic APPROACH score for area at risk assessment in ST-segment elevation myocardial infarction1340Pathological correlates of left bundle branch disease in patients with non-ischemic cardiomyopathy: a cardiovascular magnetic resonance study1342Myocardial remodelling and fibrosis in nonischaemic dilated cardiomyopathy: insights from cardiovascular magnetic resonance1411The association between fibrosis and contractile dysfunction in hypertrophic cardiomyopathy assessed by cardiovascular magnetic resonance1622Persistent myocardial inflammation due to intramyocardial haemorrhage in reperfused STEMI as a precursor to adverse LV remodelling - insights from multi-parametric mapping1566Semiquantitative analysis of low and high b value DWI for detecting myocardial edema in acute myocarditis1567Value of Cardiac MRI In Detecting Coronary Artery Disease In Newly Diagnosed Systolic Dysfunction1570Usefulness of cardiac magnetic resonance in tuberous sclerosis complex1578Papillary muscles offer further insight into hypertrophied hearts: a cardiovascular magnetic resonance study1627Diagnostic and clinical implications of CMR timing (early versus late) in patients with troponin positive acute coronary syndromes and unobstructed coronary arteries: Table 1. [O] . Upasana Tayal, Alexandros Kallifatidis, P. Garg, 2016

机译：在使用新的扩张型心肌病的患者缓和EPOSTERS1385Longitudinal应变评估加速DENSE sequence1407Simultaneous T1和T2与CABIRIA心脏定量：在4维流动的加速算法初始临床experience1423Head对头比较CMR1502Left心室功能和尺寸由混合心脏正电子发射断层摄影术评价 - 磁性共振：由两个modalities1510Left庭派生左室射血分数和心室体积的个体间的比较，在1.5和3特斯拉评估心血管磁共振 - 免费的年龄和性别effects1514Comparison呼吸心脏MRI径向技术标准的多屏气电影SSFP CMR技术的LV卷和Function1536Self-导航自由呼吸各向同性3D整个心脏相位敏感反转恢复磁共振导航仪没有检测右Ventricu心肌infarction1547Assessment的评估拉尔菌株使用心肌变形恢复半自动技术：初步经验和正常Values1586Tissue跟踪心肌变形分析和预测左室重构急性心肌infarction1589Investigating策略优化31P MRS临床心脏在3T：初始Results1620Quantitative标准的先天缺失的诊断心包心脏磁Resonance1632Widespread组织损伤急性心肌梗死时：证据先进CMR relaxometry1322Computed CT冠状动脉成像与压力心脏磁共振对症的管理吻合血管患者：成本效益研究（战略研究）1339Comparison低与高剂量钆布醇在1.5特斯拉晚钆增强成像的临床可行性，在中间型地贫心脏并发症的预测study1347Multi参数心脏核磁共振的前瞻性德穆尔心血管磁共振的ticenter Study1461Prognostic价值衍生心肌纤维化指标在住院的急性期CMR的心脏移植recipients1523The作用：改变基于CMR-paradigms1542Preoperative比分预测缺血性心脏衰竭patients1555Excellent响应速度外科左心室重建心脏再同步化后心室反应治疗与磁共振imaging1626The ECG导引作为心脏磁共振成像致心律失常性基板的在ST段抬高心肌infarction1340Pathological在风险评估经历在3.0T CMR T1映射的室性早搏contractions1649Comparison和血管造影APPROACH分数区域消融患者的预测左束支传导疾病的患者与非缺血性心肌病相关因素：心血管磁共振study1342Myocardial重塑和纤维化nonischaemic扩张型心肌病：在从在由心血管磁性resonance1622Persistent心肌炎症评估肥厚型心肌病的纤维化和收缩功能障碍之间心血管磁性resonance1411The协会由于心肌内出血景点在再灌注STEMI为先导，以不利的LV重塑 - 从低的多参数mapping1566Semiquantitative分析和高的b值DWI的见解为在心脏MRI检测冠状动脉疾病急性myocarditis1567Value在结节性硬化症complex1578Papillary肌肉初诊收缩期Dysfunction1570Usefulness心脏磁共振检测心肌水肿提供进一步的深入了解肥大心脏：心血管磁共振study1627Diagnostic和CMR定时的临床意义（早期与晚）患者肌钙蛋白阳性的急性冠脉综合征和通畅的冠状动脉：表1。

Predicting Clinical Status of Patients After an Acute Ischemic Stroke Using Random Forests

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