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首页> 外文会议>International Conference on Bio-engineering for Smart Technologies >Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer
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Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer

机译：绝经前和绝经后马来西亚女性的骨矿物质密度与乳房X线照片乳房密度的关系：有无乳腺癌的女性研究

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High mammographic breast density is an established risk factor for breast cancer whilst bone mineral density is a marker of estrogen cumulative exposure. This study was conducted to compare bone mineral density in Malaysian premenopausal and postmenopausal women; with and without breast cancer. Besides, it was to determine the relationship between bone mineral density and mammographic breast density in these groups. A cross-sectional study on 50 women above 40 years old who underwent mammogram and Dual Energy X-ray Absorptiometry was conducted at the General Hospital Kuala Lumpur for a year. Respondents were chosen using purposive sampling and women who had commenced cancer treatment were excluded from the study. The mean of selected characteristics were compared between groups using independent-t and Mann-Whitney U for continuous and categorical data respectively whilst Chi-square analysis was used to determine the association of bone mineral density and mammographic breast density. A total of 31 and 19 pre- and postmenopausal women respectively. Women with scattered fibroglandular breasts were the most affected by cancer, although, there was no statistical difference (p=0.298). There was no significant difference in women with contraceptive and/or hormone replacement therapy usage with breast density based on the classification of bone mineral density (p=0.214), cancer (p=0.344) and menstrual status (p=0.298). In conclusion, there was an adverse association between bone mineral density and mammographic breast density in both premenopausal and postmenopausal women; with and without breast cancer.
机译：乳房X光检查的高乳房密度是乳腺癌的既定危险因素，而骨矿物质密度是雌激素累积暴露的标志。这项研究的目的是比较马来西亚绝经前和绝经后妇女的骨矿物质密度。有或没有乳腺癌。此外，还需要确定这些人群中骨矿物质密度与乳房X线照片乳房密度之间的关系。在吉隆坡综合医院进行了一项针对50名40岁以上的女性的横断面研究，这些女性接受了乳房X光检查和双能X线吸收测量。使用目的性抽样选择了受访者，开始进行癌症治疗的妇女被排除在研究之外。分别使用Independent-t和Mann-Whitney U分别比较连续组和分类数据的选定特征的均值，而卡方分析用于确定骨矿物质密度与乳房X线摄影乳房密度之间的关系。绝经前和绝经后的女性分别为31和19。尽管散布的纤维腺乳腺女性受癌症影响最大，但无统计学差异（p = 0.298）。根据骨矿物质密度（p = 0.214），癌症（p = 0.344）和月经状态（p = 0.298）的分类，使用避孕药和/或激素替代疗法且乳房密度高的女性没有显着差异。总之，绝经前和绝经后妇女的骨矿物质密度与乳房X线摄影乳房密度之间存在负相关关系。有或没有乳腺癌。

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