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Effects of Doctor Networking on Diffusion of New Cancer Therapy

机译:医生网络对新疗法扩散的影响

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Cancer, which is uncontrolled cell growth in malignant tumors, has been the leading cause of death in Japan since 1981. Therefore, cancer suppression by finding novel drugs or therapies is one of the most important challenges facing the world today. Recently, new drugs including monoclonal antibodies and immune checkpoint inhibitors have been invented. However, the sales of the new drugs do not depend solely on their medical effect. There are many factors affecting the diffusion of a new cancer therapy. In this study, we focused on the attitudes and behaviors of cancer specialists in order to understand improved marketing strategies for new cancer therapies. First, we studied how a specialist decides whether or not to adopt the new therapy, by applying a qualitative comparative analysis to an interview survey of cancer specialists. Secondly, we modeled the behavior of cancer specialists toward a new therapy. Then, we simulated the diffusion of a new therapy using agent-based social simulation. Finally, the findings that can be utilized in marketing strategies were obtained. One of the most interesting findings was that the topology of the network of cancer specialists has a large effect on the diffusion of the new therapy.
机译:自1981年以来,癌症一直是日本恶性肿瘤的主要死因,而癌症是恶性肿瘤中不受控制的细胞生长。因此,通过发现新药或疗法抑制癌症是当今世界面临的最重要挑战之一。最近,已经发明了包括单克隆抗体和免疫检查点抑制剂的新药物。但是,新药的销售并不仅仅取决于它们的医疗效果。有许多因素影响一种新的癌症治疗方法的扩散。在这项研究中,我们专注于癌症专家的态度和行为,以了解新的癌症疗法的改进营销策略。首先,我们通过对癌症专家的访谈调查进行定性比较分析,研究了专家如何决定是否采用新疗法。其次,我们对癌症专家对新疗法的行为进行了建模。然后,我们使用基于代理的社交模拟来模拟一种新疗法的扩散。最后,获得了可用于营销策略的发现。最有趣的发现之一是癌症专家网络的拓扑结构对新疗法的传播有很大影响。

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