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A Thermal Energy Balance Model for Hypotension Prevention in Hemodialysis

机译:血液透析中低血压预防的热能平衡模型

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In the present paper, the authors propose a thermal energy balance model in order to prevent accidents in hemodialysis. Hemodialysis is the most common treatment for renal failure. It performs an extracorporeal blood wastes filtration taking the place of the malfunctioning kidney. Nevertheless this replacement therapy is cause of several side effects affecting the hemodynamic stability of patient. The authors focus attention on the hypotension accident. Thermal energy/heat exchanges between extracorporeal system and body might be cause of hypotension occurrence. Unfortunately, today poor importance is given to such aspects. A careful analysis of these issues has allowed authors to define a model for optimizing treatment procedures nowadays used in medical practice. In fact, most of the hemodialysis machines control automatically the dialysate solution temperature starting from peripheral body temperature measurements. Differently, the proposed approach is based on two control parameters: the predialysis patient core temperature and heat exchanges. Non-invasive temperature measurements of arterial and venous blood are obtained by estimating the thermal energy exchange. The aim of the present model is to guarantee a constant patient core temperature preventing intradialytic hypotension.
机译:在本文中,作者提出了热能平衡模型,以防止血液透析事故。血液透析是肾衰竭最常见的治疗方法。它表现出体外血液废物过滤,取代肾脏发生故障。然而,这种替代疗法是影响患者血液动力学稳定性的几个副作用的原因。作者将重点关注低血压事故。体外系统和体外的热能/热交换器可能是低血压发生的原因。不幸的是,今天对这些方面的重要性差。对这些问题的仔细分析允许作者定义了用于优化医疗实践中使用的治疗程序的模型。实际上,大多数血液透析机器自动控制从外围体温测量开始的透析液溶液温度。不同地,所提出的方法基于两个控制参数:预先估计核心温度和热交换器。通过估计热能交换来获得动脉和静脉血的非侵入式温度测量。本模型的目的是保证持续的患者核心温度,防止细胞内的低血压。

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