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首页> 外文会议>Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology >Disconnect between the Research on Lead's Effects, and Efforts to Generate a Lead Awareness and Prevention Program at a National-Level in Mexico
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Disconnect between the Research on Lead's Effects, and Efforts to Generate a Lead Awareness and Prevention Program at a National-Level in Mexico

机译：铅的影响研究与在墨西哥建立国家级铅意识和预防计划的努力之间脱节

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The documentation of lead poisoning in Mexico started at the beginning of XIX century, clearly identifying the use of traditional ceramics to prepare, store and serve food as a source of exposure. These ceramics are produced with a final layer of a lead glaze, which is ideal for the low-temperature domestic kilns. The use of these ceramics is deeply embedded in Mexican culture, but with every use in cooking or serving of food, lead leaches out. Thus, ceramic ware constitutes an important source of exposure for both the end-users and artisan-producers and their families. Much epidemiological research has been conducted by our research group to assess the toxic effects of lead exposure on a wide variety of outcomes through the ELEMENT and PROGRESS cohort studies. Our research has had an impact on lead regulation in several countries, including the U.S. and Mexico. In Mexico, the reference blood lead level for pregnant women and 0-15 year old children was 10 μg/dL until 2017, when it matched the Centers for Disease Control and Prevention (CDC) level of 5 μg/dL. Nevertheless, there is no routine surveillance program or social interventions to prevent lead exposure; furthermore, there is no public awareness of lead's toxicity. This talk will present the efforts conducted by our research group to generate supporting evidence that lead exposure is a public health problem in Mexico and should be addressed. Effects of lead exposure are subclinical, especially at low levels, and compete with other prominent health concerns such as obesity or diabetes. The strategies used by our group to generate evidence aimed at policy makers are designed in the context of scarce economic resources; therefore, lessons learned could be useful to other countries in similar situations.
机译：墨西哥铅中毒的文献始于十九世纪初，清楚地确定了使用传统陶瓷来制备，储存和用作食物的暴露来源。这些陶瓷的最后一层是铅釉，是低温家用窑炉的理想选择。这些陶瓷的使用已深深地根植于墨西哥文化中，但是在烹饪或提供食物的每一种用途中，铅都会浸出。因此，对于最终用户和手工业者及其家庭而言，陶瓷器皿是重要的暴露来源。我们的研究小组已进行了许多流行病学研究，以通过ELEMENT和PROGRESS队列研究评估铅暴露对多种结局的毒性作用。我们的研究对包括美国和墨西哥在内的多个国家的铅法规产生了影响。在墨西哥，直到2017年，孕妇和0-15岁儿童的参考血铅水平为10μg/ dL，与疾病控制与预防中心（CDC）的5μg/ dL相匹配。然而，没有常规的监测程序或社会干预措施来防止铅暴露;此外，还没有公众意识到铅的毒性。本演讲将介绍我们研究小组为获得铅暴露是墨西哥的公共卫生问题并应予以解决的支持证据而做出的努力。铅暴露的影响是亚临床的，尤其是在低水平时，并且会与其他重要的健康问题（例如肥胖症或糖尿病）竞争。我们小组用于针对决策者提供证据的策略是在经济资源匮乏的情况下设计的;因此，汲取的经验教训可能会对类似情况的其他国家有所帮助。

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