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Temperature-Related Hospital Outpatients for Cardiovascular and Respiratory Diseases in Seven Major Cities of South Korea

机译:韩国七个主要城市中与温度有关的心血管和呼吸系统疾病门诊病人

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Background: There is limited evidence on ambient temperature effects on hospital outpatients for cardiovascular respiratory diseases. This study assessed the temperature effects in seven major cities (Seoul, Busan, Incheon, Daegu, Gwangju, Daejeon and Ulsan) of South Korea Methods: A time-stratified case-crossover design was used to assess relationship of daily mean temperature with hospital visits for hypertension (110), ischemic heart disease (120-25), heart failure (150), cerebrovascular diseases (160-69), pneumonia (J12-18), allergic rhinitis (J30), asthma (J45) and chronic lower respiratory diseases (J40-44) during the period of 2008-2015. City-specific distributed lag non-linear models were fitted using a conditional Poisson regression with over-dispersion. Lag intervals up to previous 14, 21 and 28 days of exposure were considered. Relative humidity, air pressure, holiday and influenza epidemic were adjusted for. Multivariate meta-analysis was conducted. Results: We found associations between low temperature and hospital visits for cardiovascular and respiratory diseases. For instance, compared to those at 50th percentile of temperature (14.8C), the pooled cumulative associations up to previous 21 days of exposure (cumulative relative risk) at 1st percentile of temperature (-6.6C) for hospital visits for hypertension and ischemic heart diseases were 1.23 (95% CI: 1.17, 1.30) and 1.14 (95% CI: 1.05, 1,24) respectively. Compared to those at 10th percentile of temperature (-0.6C), the pooled cumulative associations at 1st percentile of temperature (-6.6C) for hospital visits for allergic rhinitis and asthma were 1.15 (95% CI: 1.07,1.25) and 1.09, (95% CI:, 1.01, 1.18) respectively. Conclusion: This study suggests that exposure to ambient low temperature increases risk of hospital visits for cardiovascular and respiratory diseases.
机译:背景:关于环境温度对心血管呼吸系统疾病对医院门诊病人影响的证据有限。这项研究评估了韩国七个主要城市(首尔,釜山,仁川,大邱,光州,大田和蔚山)的温度影响。方法:采用时间分层的病例交叉设计评估每日平均温度与就诊次数的关系适用于高血压(110),缺血性心脏病(120-25),心力衰竭(150),脑血管疾病(160-69),肺炎(J12-18),过敏性鼻炎(J30),哮喘(J45)和慢性下呼吸道疾病2008-2015年期间的疾病(J40-44)。使用带有过度分散的条件Poisson回归拟合特定于城市的分布式滞后非线性模型。考虑到之前的14、21和28天的延迟间隔。调整了相对湿度,气压,假日和流行性感冒。进行多元荟萃分析。结果:我们发现低温与心血管疾病和呼吸系统疾病的就诊之间存在关联。例如,与处于温度第50个百分点(14.8C)的人群相比,高血压和缺血性心脏病医院就诊时,在温度第1个百分点(-6.6C)之前的21天暴露量(累积相对风险)的累积累积关联疾病分别为1.23(95%CI:1.17、1.30)和1.14(95%CI:1.05、1.24)。与温度为百分之十(-0.6C)时相比,过敏性鼻炎和哮喘住院患者在温度为百分之一(-6.6C)时的累积累积关联为1.15(95%CI:1.07,1.25)和1.09, (95%CI :, 1.01,1.18)。结论:这项研究表明,暴露于环境低温下会增加心血管和呼吸系统疾病的就诊风险。

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