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Temperature-Related Hospital Outpatients for Cardiovascular and Respiratory Diseases in Seven Major Cities of South Korea

机译:韩国七大城市的温度相关医院外分门诊心血管和呼吸系统疾病

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Background: There is limited evidence on ambient temperature effects on hospital outpatients for cardiovascular respiratory diseases. This study assessed the temperature effects in seven major cities (Seoul, Busan, Incheon, Daegu, Gwangju, Daejeon and Ulsan) of South Korea Methods: A time-stratified case-crossover design was used to assess relationship of daily mean temperature with hospital visits for hypertension (110), ischemic heart disease (120-25), heart failure (150), cerebrovascular diseases (160-69), pneumonia (J12-18), allergic rhinitis (J30), asthma (J45) and chronic lower respiratory diseases (J40-44) during the period of 2008-2015. City-specific distributed lag non-linear models were fitted using a conditional Poisson regression with over-dispersion. Lag intervals up to previous 14, 21 and 28 days of exposure were considered. Relative humidity, air pressure, holiday and influenza epidemic were adjusted for. Multivariate meta-analysis was conducted. Results: We found associations between low temperature and hospital visits for cardiovascular and respiratory diseases. For instance, compared to those at 50th percentile of temperature (14.8C), the pooled cumulative associations up to previous 21 days of exposure (cumulative relative risk) at 1st percentile of temperature (-6.6C) for hospital visits for hypertension and ischemic heart diseases were 1.23 (95% CI: 1.17, 1.30) and 1.14 (95% CI: 1.05, 1,24) respectively. Compared to those at 10th percentile of temperature (-0.6C), the pooled cumulative associations at 1st percentile of temperature (-6.6C) for hospital visits for allergic rhinitis and asthma were 1.15 (95% CI: 1.07,1.25) and 1.09, (95% CI:, 1.01, 1.18) respectively. Conclusion: This study suggests that exposure to ambient low temperature increases risk of hospital visits for cardiovascular and respiratory diseases.
机译:背景:关于心血管呼吸疾病的医院门诊患者的环境温度效应存在有限的证据。本研究评估了韩国七大城市(首尔,釜山,仁川,大邱,广州,大邱和蔚山)的温度效应:时间分层案例交叉设计用于评估每日平均温度与医院访问的关系对于高血压(110),缺血性心脏病(120-25),心力衰竭(150),脑血管疾病(160-69),肺炎(J12-18),过敏性鼻炎(J30),哮喘(J45)和慢性低呼吸道2008 - 2015年期间疾病(J40-44)。使用具有过度分散的条件泊松回归来安装城市特定的分布式滞后非线性模型。考虑了前面的滞后间隔,21,21天和28天的接触。调整了相对湿度,气压,假期和流感流行病。进行多元荟萃分析。结果:我们发现了低温与呼吸疾病的低温和医院访问之间的关联。例如,与第50百分位的温度(14.8℃)的那些相比,汇集累积关联的融合缔结的融合缔促暴露(累积相对风险)在高温(-6.6℃)中,用于高血压和缺血性心脏的医院访问疾病分别为1.23(95%CI:1.17,17,17,1130)和1.14(95%CI:1.05,1,24)。与温度(-0.6℃)的第10百分位数相比,高温(-6.6℃)的汇集累积关联(-6.6℃),用于过敏性鼻炎和哮喘的医院访问为1.15(95%CI:1.07,1.25)和1.09, (95%CI:,1.01,1.18)。结论:本研究表明,暴露于环境低温,增加了医院访问心血管和呼吸系统疾病的风险。

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