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A Compact System for Blood Impedance Measurements for ROS Evaluation

机译:用于ROS评估的紧凑型血液阻抗测量系统

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The aim of this research is to provide a compact, low cost and reliable impedance measurement system for the analysis of biological fluids, and specifically of blood samples, based on impedance spectroscopy measurements in the frequency range 1 kHz-100 kHz. In particular, the applicability of the developed instrument to the detection of Reactive Oxygen Species (ROS) in blood is explored. ROS have been known to display prominent roles in the pathogenesis of several acute and chronic disorders and in inflammatory conditions. In this paper we show that the proposed system can provide similar information about the ROS concentration in blood subpopulations as other expensive and time consuming techniques, leading to great time savings, and opening the possibility of screening programs based on oxidative stress monitoring.
机译:这项研究的目的是基于1 kHz-100 kHz频率范围内的阻抗谱测量,提供一种紧凑,低成本和可靠的阻抗测量系统,用于分析生物流体,尤其是血液样本。特别是,探索了开发的仪器在检测血液中活性氧(ROS)方面的适用性。已知ROS在几种急性和慢性疾病的发病机理以及炎性疾病中显示出显著作用。在本文中,我们证明了所提出的系统可以提供与其他昂贵且费时的技术类似的有关血液亚群中ROS浓度的信息,从而节省大量时间,并为基于氧化应激监测的筛查程序提供了可能性。

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