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Clinical Kidney Volume Measurement Accuracy Using NEFROVOL

机译:使用NEFROVOL进行临床肾脏体积测量的准确性

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In case of Autosomal Dominant Polycystic Kidney Disease, kidney volume provides an indicator of disease progression. To estimate such growth, ultrasound is a safe and low cost imaging technique, albeit limited to regular shape organs. We developed a new measurement method with skin silicon templates to obtain parallel and equidistant images of the kidney, as a series of transverse sections. With NEFROVOL software, nephrologists are able to contour kidney boundaries, reconstruct a 3D renal representation and calculate its volume, including extremely irregularly shaped. We conducted a phantom study with sweet potatoes, volunteers and patients with transplanted or enlarged kidneys. The volumetric error decreases from 22% to 15% as the number of sections increases from 4 or 5 to 6 or 9 for patients and potatoes respectively. Best precision was estimated with 9 sections for 15 cm sweet potatoes and 6 sections for 11 cm healthy kidneys. The best skin template is one with two positions for the internal frame, with one section every 1.5 cm.
机译:在常染色体显性多囊肾疾病的情况下,肾脏体积是疾病进展的指标。为了估计这种生长,尽管限于规则的形状器官,超声是一种安全且低成本的成像技术。我们使用皮肤硅模板开发了一种新的测量方法,以获取肾脏的平行和等距图像(一系列横截面)。借助NEFROVOL软件,肾脏病专家能够勾勒出肾脏边界轮廓,重建3D肾脏表现并计算其体积,包括形状极其不规则的肾脏。我们对甘薯,志愿者和肾脏移植或肾脏肿大的患者进行了幻像研究。当患者和马铃薯的切片数从4或5增加到6或9时,体积误差从22%降低到15%。最佳精度估计为9个15厘米的甘薯切片和6个11厘米的健康肾脏切片。最好的皮肤模板是内部框架有两个位置的模板,每1.5厘米有一节。

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