Post occlusive hyperaemic effect of tissue under static and dynamic loading conditions using laser perfusion imager

机译：静态和动态负载条件下组织的闭塞性高血压作用使用激光灌注成像仪

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Post-occlusive hyperaemic response of cutaneous microcirculation at a site on the volar surface of the forearm 4-5 cm distal to the elbow has been evaluated using the laser Doppler perfusion imager. Nine healthy young subjects were studied following three types of externally applied loading conditions: (static) pressure only, combination of pressure and shear, and (dynamic) combination of pressure and cyclic shear; each applied for a duration of 3 minutes. Pressure loading of 172 mmHg was applied, with and without the application shear stresses. For dynamic loading, cyclic shear was applied at a rate of 1 Hz. Multiple scans were conducted over an area of 1400 mm/sup 2/ during the first 400 to 600 seconds of the post-occlusion period. Peak hyperaemic flow was established immediately after occlusion for the static loading conditions, while this peak flow (at 204% resting level) was maintained for a longer period of time after the application of cyclic shear. The half-life of hyperaemic response was observed within 100 seconds post-occlusion after static loading but was about doubled after dynamic loading. It was also found that hyperaemic flow did not decay following a single exponential decay pattern, but can be better represented with two exponential decay time constants. The observed adversity effect of dynamic loading to tissue prompts a reevaluation of the strategy in pressure sore prevention.

机译：使用激光多普勒灌注成像器评估了在前臂4-5cm的远端的前臂4-5cm的Volar表面上的皮肤微循环的后闭塞性过度响应。研究了九种健康的年轻受试者，在外部施加的三种类型的外部施加的装载条件下进行:(静态）压力，压力和剪切的组合，（动态）压力和循环剪切的组合;每个持续时间为3分钟。应用172mmHg的压力负载，有和没有施加剪切应力。对于动态负载，以1 Hz的速率施加循环剪切。多次扫描在闭塞后期的前400至600秒的前400至600秒内进行超过1400mm / sup 2 /。在闭塞静态负载条件下立即建立峰度过度流动，而在施用循环剪切后，该峰值流动（在204％静止水平）保持较长时间。在静电载荷后100秒内观察到过度震作反应的半衰期，但在动态载荷后大约加倍。还发现，在单个指数衰减模式之后，大蠕动并未衰减，但是可以更好地用两个指数衰减时间常数表示。动态载荷对组织的观察到逆变效应促使对压力疼痛预防策略进行重新评估。

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《Annual International Conference of the IEEE Engineering in Medicine and Biology Society》|1998年||共3页
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Tam E.W.C.; Mak A.F.T.; Institute of Electric and Electronic Engineer;
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中图分类自动化技术、计算机技术;
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3. Reply: Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: A Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction [J] . To Cynthia, Rees-Lee Jacqueline E., Gush Rodney J., Plastic and reconstructive surgery . 2019,第5期

机译：回复：激光散斑成像术中的术中组织灌注测量：潜在的辅助助剂在免费襟翼乳房重建中减少术后并发症
4. Post occlusive hyperaemic effect of tissue under static and dynamic loading conditions using laser perfusion imager [C] . Tam, E.W.C., Mak, Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE . 1998

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5. Dynamic Imaging of Tissue Perfusion Using Ultrasound Contrast Agents. [D] . Du, Juan. 2016

机译：使用超声造影剂对组织灌注进行动态成像。
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Post occlusive hyperaemic effect of tissue under static and dynamic loading conditions using laser perfusion imager

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