Post occlusive hyperaemic effect of tissue under static and dynamic loading conditions using laser perfusion imager

机译：在静态和动态负荷条件下组织的闭塞性充血后效果使用激光灌注成像仪

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Post-occlusive hyperaemic response of cutaneous microcirculation at a site on the volar surface of the forearm 4-5 cm distal to the elbow has been evaluated using the laser Doppler perfusion imager. Nine healthy young subjects were studied following three types of externally applied loading conditions: (static) pressure only, combination of pressure and shear, and (dynamic) combination of pressure and cyclic shear; each applied for a duration of 3 minutes. Pressure loading of 172 mmHg was applied, with and without the application shear stresses. For dynamic loading, cyclic shear was applied at a rate of 1 Hz. Multiple scans were conducted over an area of 1400 mm/sup 2/ during the first 400 to 600 seconds of the post-occlusion period. Peak hyperaemic flow was established immediately after occlusion for the static loading conditions, while this peak flow (at 204% resting level) was maintained for a longer period of time after the application of cyclic shear. The half-life of hyperaemic response was observed within 100 seconds post-occlusion after static loading but was about doubled after dynamic loading. It was also found that hyperaemic flow did not decay following a single exponential decay pattern, but can be better represented with two exponential decay time constants. The observed adversity effect of dynamic loading to tissue prompts a reevaluation of the strategy in pressure sore prevention.

机译：使用激光多普勒灌注成像仪评估了前臂掌表面距肘部4-5 cm处的皮肤微循环的闭塞后充血反应。对九名健康的年轻受试者进行了以下三种外部施加负荷条件的研究：仅（静态）压力，压力和剪切力的组合以及压力和循环剪切力的（动态）组合;每个应用程序持续3分钟。在施加和不施加剪切应力的情况下施加172 mmHg的压力载荷。对于动态加载，以1 Hz的速率施加循环剪切。在闭塞后的前400至600秒内，对1400 mm / sup 2 /的区域进行了多次扫描。在静态载荷条件下，闭塞后立即建立了峰值高通气流量，而在施加周期性剪切后，该峰值流量（静息水平为204％）保持了较长的时间。在静态负荷后100秒钟内观察到充血反应的半衰期，但在动态负荷后约半倍。还发现高氧流不会按照单个指数衰减模式衰减，而是可以用两个指数衰减时间常数更好地表示。观察到的动态负荷对组织的逆境效应促使人们重新评估预防压疮的策略。

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《Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE》|1998年|P.2294-2296|共3页
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Tam; E.W.C.; Mak; A.F.T.;
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中图分类无线电电子学、电信技术;
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3. Reply: Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: A Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction [J] . To Cynthia, Rees-Lee Jacqueline E., Gush Rodney J., Plastic and reconstructive surgery . 2019,第5期

机译：回复：激光散斑成像术中的术中组织灌注测量：潜在的辅助助剂在免费襟翼乳房重建中减少术后并发症
4. Post occlusive hyperaemic effect of tissue under static and dynamic loading conditions using laser perfusion imager [C] . Tam E.W.C., Mak A.F.T., Institute of Electric and Electronic Engineer Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 1998

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5. Dynamic Imaging of Tissue Perfusion Using Ultrasound Contrast Agents. [D] . Du, Juan. 2016

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Post occlusive hyperaemic effect of tissue under static and dynamic loading conditions using laser perfusion imager

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