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首页> 外文会议>International symposium on ceramics in medicine >Bonding behavior of bioactive bone cement in segmental replacement of rabbit tibia: comparison with PMMA bone cement
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Bonding behavior of bioactive bone cement in segmental replacement of rabbit tibia: comparison with PMMA bone cement

机译：生物活性骨水泥在兔胫骨分段替代的粘结行为：与PMMA骨水泥的比较

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We have developed a bioactive bone cement (BABC) which consists of apatite and wollastonite containing glass-ceramic (AW-GC) powder and bisphenol-A-glycidyl dimethacrylate (Bis-GMA)-based resin. In the present study, the effectiveness of the BABC for repair of segmental bone defects under load-bearing conditions was examined using a rabbit-tibia model. Polymethylmethacrylate (PMMA) bone cement was used as a control. A 15-mm-length of bone was resected from the middle of the shaft of the tibia, and the tibia was fixed by two Kirschner wires. The defects were replaced by cement. Each cement was used in 12 rabbits, with six rabbits each being killed at 12 and 25 weeks after surgery and the tibia containing the bone cement was excised and tension-tested. At both the intervals studied, the failure loads of the BABC were significantly higher than those of the PMMA cement. The BABC was in direct contact with bone, whereas soft tissue was observed between cement and bone in all PMMA cement specimens. Results indicated that the BABC was useful as a bone substitute under load-bearing conditions.
机译：我们开发了一种生物活性骨水泥（BABC），其由含有玻璃 - 陶瓷（AW-GC）粉末和双酚-A-缩水甘油基二甲基丙烯酸酯（BIS-GMA）的树脂组成的生物活性骨水泥（BABC）。在本研究中，使用兔胫骨模型检查BABC用于修复承载条件下的节段性骨缺陷的有效性。将聚甲基丙烯酸甲酯（PMMA）骨水泥用作对照。从胫骨的轴的中间切除了15毫米的骨头，胫骨由两个kirschner线固定。缺陷被水泥取代。每个水泥用于12只兔子，每只兔子在手术后12和25周杀死，并且切除含有骨水泥的胫骨并进行张力测试。在研究的间隔中，BABC的故障载荷显着高于PMMA水泥的负载。 BABC与骨直接接触，而在所有PMMA水泥样本中的水泥和骨之间观察到软组织。结果表明，BABC可用作承载条件下的骨替代品。

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