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POST-TRANSCRIPTIONAL GENE REGULATION: RNA-PROTEIN INTERACTIONS, RNA PROCESSING, MRNA STABILITY AND LOCALIZATION

机译:转录后基因调节:RNA-蛋白质相互作用,RNA加工,mRNA稳定性和定位

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The goal of our workshop is to introduce some recent work in the area of post-transcriptional regulation to a wider computational community, discuss some of the unique computational problems faced in this area, and to present some preliminary solutions to these problems. In particular, we will focus on emerging computational and large-scale experimental strategies (e.g. microarray and deep sequencing) for investigating aspects of gene regulation at the post-transcriptional level, with an emphasis on the identification and characterization of the cis- and trans-acting RNA and protein components involved. We will also be exploring new developments in computational methods to detect and characterize cis-regulatory signals encoded in mRNAs.
机译:我们的研讨会的目标是在更广泛的计算社区介绍一下转录后规定的一些工作,讨论该领域面临的一些独特的计算问题,并为这些问题提出一些初步解决方案。特别是,我们将专注于新出现的计算和大规模的实验策略(例如微阵列和深度测序),用于研究后转录后水平的基因调节的方面,重点是CIS-和转发的鉴定和表征作用RNA和蛋白质组分。我们还将探索计算方法的新发展,以检测和表征MRNA编码的CIS-Convistation信号。

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