Mutagenic Action of Heavy Charged Particles: Cross Sections, RBE and Molecular Alterations

机译：强带状粒子的致突变性作用：横截面，RBE和分子改变

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Heavy charged particles constitute an important part of cosmic radiation, and their action may thus present a substantial hazard to astronauts. There are no data on their effects in humans, so risk estimates have to be inferred from radiobiological experiments. Mutations play an essential role in carcinogenesis; knowledge of their induction probability could thus add to the fundamentals of risk assessment. We have systematically studied mutation induction by heavy ions and recently started to characterise their molecular pattern by polymerase chain reaction (PCR). Results are reviewed, and RBE values compared to the recent ICRP recommendations.

机译：大致带电粒子构成了宇宙辐射的重要组成部分，因此它们的作用可能因此对宇航员造成了大量的危害。没有关于人类效果的数据，因此必须从放射生物学实验中推断出风险估计。突变在致癌物中发挥着重要作用;因此，对其归纳概率的了解可以增加风险评估的基本面。我们系统地研究了重离子的突变诱导，最近开始通过聚合酶链反应（PCR）表征其分子模式。与最近的ICRP建议相比，审查了结果，rbe价值观。

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《International congress of radiation research》|2000年||共4页
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Juergen Kiefer;
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中图分类放射性元素、放射化学;
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1. M-X-ray production cross sections of heavy elements by charged-particle impact [J] . Takeshi Mukoyama Nuclear Instruments & Methods in Physics Research . 2017,第octa1期

机译：通过带电粒子撞击产生重元素的M-X射线横截面
2. Investigation of the deuteron induced nuclear reaction cross sections on lutetium up to 50 MeV: review of production routes for Lu-177, Hf-175 and Hf-172 via charged particle activation [J] . Tarkanyi F., Takacs S., Ditroi F., Journal of Radioanalytical and Nuclear Chemistry: An International Journal Dealing with All Aspects and Applications of Nuclear Chemistry . 2020,第3期

机译：氘诱导核反应横截面的抑制率高达50 meV：通过带电粒子活化审查Lu-177，HF-175和HF-172的生产路线
3. Reference Cross Sections for Charged-particle Monitor Reactions [J] . A. Hermanne, A.V. Ignatyuk, R. Capote, Nuclear Data Sheets . 2018,第feba期

机译：带电粒子监测器反应的参考截面
4. Mutagenic Action of Heavy Charged Particles: Cross Sections, RBE and Molecular Alterations [C] . Juergen Kiefer International congress of radiation research . 2000

机译：强带状粒子的致突变性作用：横截面，RBE和分子改变
5. Measurements of secondary charged particle fragmentation cross sections produced by high energy heavy ions using silicon strip detectors. [D] . Stephens, Daniel Leon, Jr. 2002

机译：使用硅条检测器测量由高能重离子产生的次级带电粒子破碎截面。
6. Molecular dynamics simulation of highly charged proteins: Comparison of the particle-particle particle-mesh and reaction field methods for the calculation of electrostatic interactions [O] . Raimundo Gargallo, Philippe H. Hünenberger, Francesc X. Avilés, 2003

机译：高电荷蛋白质的分子动力学模拟：比较粒子-粒子-粒子-网格和反应场方法以计算静电相互作用
7. Relativistic Calculations of the Excitation Cross Sections of Hydrogen-Like Ions by Heavy Charged-Particle Impact [O] . Mukoyama Takeshi 1986

机译：重带电粒子碰撞氢样离子激发截面的相对论计算
8. Production Cross-Sections for Charged Particle Interactions in Matter Relevant to Bio-Medical Applications. Talk Given to the Charged Particle Physics Dosimetry Group Workshop at Los Alamos, 17 March 1978 [R] . Reading, D. H. 1978

机译：与生物医学应用相关的带电粒子相互作用的生产截面。 1978年3月17日在洛斯阿拉莫斯召开的带电粒子物理剂量学小组研讨会

Mutagenic Action of Heavy Charged Particles: Cross Sections, RBE and Molecular Alterations

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