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SEPSIS SEPTIC SHOCK: RECOGNITION TREATMENT

机译:脓毒症和腐败休克:识别与治疗

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摘要

Systemic inflammation associated with an infectious process is a common cause of critical illness in veterinary medicine. Sepsis, severe sepsis, and septic shock are terms that have been used to define a continuum of systemic response to infection. Currently,SIRS describes a systemic response to a severe insult and consists of changes in two out of the following criteria: 1. Heart rate (tachycardia); 2. Respiratory rate (tachypnea); 3. Temperature (fever or hypothermia); 4. White blood cell count (leukocytosis, leucopenia, or excessive bands). Temperature: Pyrogens released by macrophages in response to inflammatory cytokines (tumor necrosis factor and interleukin 1) lead to changes in baseline temperature at the level of the thermoregulatory centerin the hypothala-mus. Studies suggest that fever may have a protective role in sepsis. Hypothermia may also occur, although the exact incidence and prognostic implication in veterinary sepsis is unknown. It has been suggested that hypothermia is associated with altered immune function and may contribute to increased mortality in sepsis.
机译:与感染过程有关的全身性炎症是兽药危重病的常见原因。败血症,严重败血症和感染性休克是已被用来定义感染全身性反应的连续条款。目前,SIRS描述了一个严重损伤全身应答和由在三分之二的以下标准的变化:1.心率(心动过速); 2.呼吸速率(呼吸急促); 3.温度(发热或体温过低); 4.白细胞计数(白细胞增多,白细胞减少症,或过度频带)。温度:热原响应于炎性细胞因子(肿瘤坏死因子和白细胞介素1)铅释放由巨噬细胞,以改变基线温度在体温调节centerin的hypothala-亩的水平。研究表明,发烧可能在脓毒症的保护作用。低温也可能会出现,但在兽医败血症确切发病率和预后的影响是未知的。有人认为,低温与改变免疫功能相关联,并在脓毒症可能有助于增加死亡率。

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