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Combining SPOT synthesis and native chemical ligation to generate large arrays of small protein domains

机译：结合斑点合成和本地化学结扎，产生大型小蛋白域阵列

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摘要

We present a novel approach for the construction of large arrays of synthetic protein domains.A combination of SPOT synthesis and native chemical ligation was applied to generate 6859 variants of the hYAP WW protein domain consisting of 38 amino acids.

机译：我们介绍了一种新的合成蛋白域阵列构建方法。施加斑点合成和天然化学连接的组合，以产生由38个氨基酸组成的Hyap WW蛋白域的6859个变体。

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《the International Peptide Symposium》|2001年||共2页
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Florian Toepert; Tobias Knaute; Stefan Guffler; Jens Schneider-Mergener;
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Combining SPOT synthesis and native chemical ligation to generate large arrays of small protein domains

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