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Development of Revolutionizing Methods for Hybrid-Type Artificial Organs by Means of Bioceramics and Biomechanics

机译:用生物陶瓷和生物力学制定杂交型人工器官的革命性方法

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The phylogenetic transition of branchiae into the lung as well as the migration of hemopoietic activity from the spleen to the bone marrow cavity demonstrate the concurrent evolutionary changes of organs structures and functions in vertebrates in response to the effect of gravity during terrestrialization from a water environment. The present study introduces a hybrid-type artificial bone marrow chamber that uses sintered hydroxyapatite (HA) and titanium electrode, which is able to induce hemopoietic nest formation in conjunction with osteogenesis not only heterotopically in mammalian muscle, but heterospecifically in archetype vertebrates, which have no bone marrow hemopoiesis in inner skeletons (1-2). As well the gomphotic tooth system developed during the third revolution of the vertebral evolution by biomechanical stimuli, i.e., by corresponding of teeth and jawbones of animals to the masticatory movements. The authors developed artificial root of corrugated cone shape using sintered compact hydroxyapatite (HA), which could induce to be gomphotic as well as ankylotic binding system depending on biomechanical stimuli of occlusal function or complete rest of implanted root after operation (3-7). Following results are obtained: Bone marrow hemopoiesis in artificial chambers could be observed heterotopically in all cases. Gomphotic artificial roots with cementum were developed by biomechanical stimuli in the solid diet group. Ankylotic artificial roots were obtained in complete rest roots by the soft diet group.
机译:鳃进入肺部的系统发育过渡以及脾骨髓腔中血液活性的迁移证明了脊椎动物的同时结构和功能的同时进化变化,响应于水环境中的陆地化过程中的重力。本研究介绍了一种杂交型人工骨髓室,其使用烧结羟基磷灰石(HA)和钛电极,其能够与骨肉肌肉中不仅具有骨肉肌肉的溶血性巢形成,而是在原型脊椎动物中的异常杂散。内骨骼中没有骨髓血液血液(1-2)。本着生物力学刺激在椎体刺激的第三次旋转期间,即通过将动物的牙齿和颚骨对应到咀嚼运动,以及对咀嚼运动的第三次旋转期间开发的。作者使用烧结的紧凑羟基磷灰石(HA)开发了波纹锥形形状的人造根,其可诱导是根据咬合功能的生物力学刺激或植入术后植入根的生物力学刺激(3-7)的生物力学刺激。得到以下结果:在所有情况下,可以在所有情况下异常地观察人工腔室中的骨髓血液血液。用豆类毒液的含有豆类的含有豆类的含有豆类的人工根源。通过软饮食组完全休息根部获得了吻合的人工根源。

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