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Low intensity laser irradiation stimulates healing in stressed models

机译:低强度激光照射刺激压力模型中的愈合

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Wound healing in diabetic patients remains a complicated problem and there is a compelling need for the development of new, safe, reliable therapies. This study looked at the effect of low intensity laser irradiation (LILI) on diabetic wound healing in vitro. Induced diabetic wounded and hypoxic human fibroblast cells were irradiated at 636 nm with 5 J/cm2. Post-irradiation stressed cells showed increased viability and proliferation and a decrease in apoptosis and pro-inflammatory cytokines (IL-1β and TNF-α). The models used are sufficient to produce measurable effects as compared to normal cells. LILI positively effects wound healing in stressed models, normalises cellular function, and directs cells into cell survival pathways.
机译:糖尿病患者的伤口愈合仍然是一个复杂的问题,有必要开发新的安全,可靠的疗法。 本研究研究了低强度激光辐照(LILI)对体外糖尿病伤口愈合的影响。 诱导的糖尿病伤员和缺氧人成纤维细胞在636nm下用5J / cm 2照射。 后辐射后胁迫细胞显示出增加的活力和增殖以及细胞凋亡和促炎细胞因子的降低(IL-1β和TNF-α)。 与正常电池相比,所使用的模型足以产生可测量的效果。 Lili积极影响伤口愈合在应激模型中,归一性细胞功能,并将细胞引导到细胞存活途径中。

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