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Dissolvable and Asymmetric Hydrogels as Components for Microfluidic Systems

机译:可溶解和不对称水凝胶作为微流体系统的组分

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We demonstrate the development of novel hydrogel materials by controlling the crosslink density. A pH-responsive hydrogel with a crosslink density gradient, created by laminar flow and diffusion, showed asymmetric swelling during volume transition. Hydrogels with cleavable crosslinkers have also been designed and fabricated inside microfluidic channels. Upon exposure to reagents that can chemically cleave such crosslinkers, the de-crosslinked hydrogels dissolve completely, making them promising as sacrificial structures and sensors for microfluidics.
机译:我们通过控制交联密度来证明新型水凝胶材料的发展。具有由层流和扩散产生的具有交联密度梯度的pH响应水凝胶,在体积转变期间显示出不对称的肿胀。还在微流体通道内设计和制造具有可切割交联剂的水凝胶。在暴露于可以化学切割这种交联剂的试剂后,将脱粘的水凝胶完全溶解,使它们充当作为微流体的牺牲结构和传感器。

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