CHEMOTHERAPY UTILIZING ABSORPTION FROM LIVER SURFACE: POSSIBILITY OF LIVER SITE-SELECTIVE 5-FU DELIVERY IN RATS

机译：使用肝脏表面吸收的化疗：肝脏位点的可能性 - 选择性5-FU递送

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The present study was undertaken to elucidate the possibility of the liver site-selective drug delivery after application to the liver surface in rats. 5-FU was absorbed 69.1% of dose in 360 min. The plasma concentration was very low until 360 min. 5-FU accumulated preferentially around the administration site.

机译：本研究旨在阐明在施用到肝脏表面的大鼠后肝脏位点选择性药物递送的可能性。在360分钟内吸收了69.1％的剂量的5-FU。等离子体浓度非常低至360分钟。优先在给药地点累计5-FU。

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《Annual meeting of the Controlled Release Society》|2002年||共2页
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Y.Kodama; K.Nishida; M.Shimomura; R.Fujiwara; S.Kawakami; M.Nakashima; H.Sasaki; T.Sakaeda; J. Nakamura;
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中图分类制药化学工业;
关键词
site-specific delivery; targeted delivery; tumor drug delivery;

机译：特定网站递送;有针对性的交付;肿瘤药物递送;
入库时间 2022-08-20 19:31:08

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3. Influence of liver disease on phenolsulfonphthalein absorption from liver surface to examine possibility of direct liver surface application for drug targeting. [J] . Nishida K, Honda T, Nakashima M, Biological & pharmaceutical bulletin . 2003,第7期

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4. CHEMOTHERAPY UTILIZING ABSORPTION FROM LIVER SURFACE: POSSIBILITY OF LIVER SITE-SELECTIVE 5-FU DELIVERY IN RATS [C] . Y.Kodama, K.Nishida, M.Shimomura, Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

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CHEMOTHERAPY UTILIZING ABSORPTION FROM LIVER SURFACE: POSSIBILITY OF LIVER SITE-SELECTIVE 5-FU DELIVERY IN RATS

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