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Efficacy of a single dose of M+pac~(R): Onset of immunity, duration of immunity; and efficacy in pigs with maternally-derived antibodies

机译:单剂量m + pac〜(r)的疗效:免疫发作,免疫持续时间;猪的疗效与母体衍生抗体的疗效

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It has previously been demonstrated that the duration of immunity after a single dose of SPAH's Mycoplasma Hyopneumoniae Bacterin, M+Pac, is at least 4 months. The purpose of these studies was to evaluate the onset and 24-week duration of immunity andto evaluate efficacy of the product in pigs with high levels of maternally-derived antibodies (MDA) at the time of vaccination. Because a single vaccination does not elicit a strong humoral antibody response to M. hyopneumoniae, antibodies in bronchiolar alveolar lavage (BAL) fluids were evaluated, as it has been reported that local antibodies may be an important component of the protective immune response to mycoplasma pneumonia.
机译:先前已经证明,在单一剂量的SPAH的支原体渗透蛋白,M + PAC后,免疫持续时间至少为4个月。这些研究的目的是评估发病和24周的免疫持续时间,并在疫苗接种时评估具有高水平母动衍生的抗体(MDA)的猪的疗效。因为单个疫苗接种不引起对M.吞咽肺炎的强液体抗体反应,所以评估了支气管肺泡灌洗(BAL)液体的抗体,因为据报道,局部抗体可能是对支原体肺炎的保护性免疫应答的重要组成部分。

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