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Clinical efficacy and safety of native bio-absorbable polymer Rapamycin-eluting stent (Excel stent) for Chinese patients with coronary artery disease

机译:生物可吸收聚合物雷帕霉素洗脱支架(Excel支架)对冠心病患者的临床疗效和安全性

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Objective: To observe the clinical efficacy and safety of native bioabsorbable polymer Rapamycin eluting stent (Excel stent) for treating coronary artery disease (CAD). Methods: From February 2007 to October 2008, a total of 127 consecutive patients with CAD who received Excel stent implantation, 185 Excel stents were implanted in 152 criminal-related arteries. Follow up through out-patient department and telephone equipment was extended from 3 months to 6 months, to observe the improvement of clinical symptoms and incidence of cardiovascular events during hospitalization and follow-up period. Results: All the stents were implanted successfully with no MACE including additional revascularization of the index target lesion on operations. Clinical follow up showed that, among 127 patients, clinical symptoms were completely remission in 66 patients(52.0%), apparently remission in 55 patients(43.3%), partially remission in 2 patients(1.5%), unchanged in 3 patients(2.4%), only one patient(0.8%) felt aggravated. Total effective rate was 96.9%. Among 127 patients, one patient suffered congestive heart failure, and no one suffered myocardial infarction, coronary artery bypass or sudden death. Conclusions: Implantation of the Excel stents in patients with CAD is safe and feasible. Excel stent has a favorable clinical efficacy.
机译:目的:观察天然生物可吸收聚合物雷帕霉素洗脱支架(Excel支架)治疗冠状动脉疾病(CAD)的临床疗效和安全性。方法:2007年2月至2008年10月,共有127名连续127名患有Excel支架植入的CAD患者,植入了152例犯罪相关动脉。通过远程患者部门和电话设备延伸到3个月至6个月,观察住院期间和随访期间心血管事件的临床症状和发病率的提高。结果:所有支架均成功植入,没有坐标,包括在运营中的指数目标病变的额外血运重建。临床后续表明,在127名患者中,临床症状在66名患者中完全缓解(52.0%),55例患者显然缓解(43.3%),2例患者部分缓解(1.5%),3例患者不变(2.4%) ),只有一个患者(0.8%)感到加重。总有效率为96.9%。在127名患者中,一名患者患有充血性心力衰竭,没有人患心肌梗死,冠状动脉旁路或猝死。结论:CAD患者植入Excel支架是安全可行的。 Excel支架具有良好的临床疗效。

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