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首页> 外文会议>European Congress of Neurosurgery >Ablative Stereotactic Surgery Improves Manual Performance Time in Parkinson's Disease
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Ablative Stereotactic Surgery Improves Manual Performance Time in Parkinson's Disease

机译：消化的立体定向手术在帕金森病中提高了手动性能时间

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摘要

The objective of this study was to determine the influence of stereotactic ablative surgical interventions on the time required for the performance of manual tasks in patients with Parkinson's disease (PD). Therapeutic effects resulting from stereotactic lesions of the basal ganglia (pallidotomy and combined pallidothalamotomy) were analyzed in 28 consecutive patients with PD. The speed of performance of handwriting and drawing were assessed at four timepoints: before the operation, and 2 days, 3 months and 6 months postoperatively. An international standard scale (modified by Fahn) was employed to evaluate the effectiveness of the surgical interventions. According to their symptomatology, the patients were divided into 2 groups. Those in group A were characterized mainly by hypo- or akinesia, rigidity, "on/off fluctuation" and L-dopa-induced dyskinesia. In this group, pallidotomy was performed. The patients in group B exhibited not only the above symptoms and signs, but also severe resting tremor. They were treated by pallidothalamotomy. The time of performance of the manual tasks diminished significantly in all cases in both groups (Student's T test: p< 0.0001), i.e. significant improvements ensured in the speed of handwriting and drawing.
机译：这项研究的目的是确定立体定向消融手术干预上的手动任务患者帕金森病（PD）的性能所需的时间的影响。从基底节（苍白球和组合pallidothalamotomy）的立体定向损害所造成的治疗效果在连续28名PD患者进行分析。的手写和绘图性能速度分别在四个时间点评估：操作前，2天，3个月和6个月后。的国际标准标度（由法恩改性）中的溶液来评估手术干预的有效性。根据他们的症状，患者被分为2组。那些在A组主要特征是低渗或运动不能，刚性，“开/关波动”和L-多巴诱导的运动障碍。在这一组中，进行苍白球切开术。在B组的患者表现不仅上述症状和体征，而且还严重静止性震颤。他们被pallidothalamotomy处理。的人工作业性能的时间在所有情况下，两组显著减少（学生T检验：p <0.0001），即显著改善手写和绘图的速度保证。

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