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Effects of Tissue Factor Pathway Inhibitor and Antlthrombin on Thrombin Generation in Tissue Factor-actiwated Cord Plasma

机译：组织因子途径抑制剂和抗细胞间抑制作用对组织因子致脊髓等离子体血栓形成的影响

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Despite of low concentrations of clotting factors, newborns have an excellent hemostasis. Neonates have good wound heeling and show no increased bleeding during surgery. Thus, it was the aim of our study to investigate whether low concentrations of the anticoagulatory proteins tissue factor pathway inhibitor (TFPI) and antithrombin (AT) compensate for low levels of procoagulatory proteins. In contrast to the routine determinations of clotting parameter, clotting was initiated by applying low concentrations of lipidated tissue factor (TF).

机译：尽管浓度低凝血因素，但新生儿具有优异的止血。新生儿有良好的伤口后跟，并且在手术期间没有增加出血。因此，我们的研究旨在研究抗凝蛋白组织因子途径抑制剂（TFPI）和抗凝血酶（AT）的低浓度是否补偿了低水平的胰腺炎蛋白质。与凝血参数的常规测定相反，通过施加低浓度的脂质组织因子（TF）来引发凝血。

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《Hemophilie-Symposion》|2003年||共7页
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G. Cvirn; S. Gallistl; B. Leschnik; L. Giradi; W. Muntean;
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中图分类出血性疾病;
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1. Concizumab, an anti-tissue factor pathway inhibitor antibody, induces increased thrombin generation in plasma from haemophilia patients and healthy subjects measured by the thrombin generation assay [J] . Waters E. K., Sigh J., Friedrich U., Haemophilia: the official journal of the World Federation of Hemophilia . 2017,第5期

机译：抑制抗组织因子途径抑制剂抗体，诱导来自血糖患者的血浆中血浆血浆产生的增加，并通过凝血酶产生测定测量的健康受试者
2. A Neutralizing Monoclonal Antibody (PF06741086) Against Tissue Factor Pathway Inhibitor in Combination with Activated Prothrombin Complex Concentrate Increases Hemostasis in Inhibitor Hemophilia Plasmas without Excessive Thrombin Generation [J] . Rakhe Swapnil, Bowley Sheryl, Murphy John E., Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：与活化凝血酶复合物浓缩物联合组织因子途径抑制剂的中和单克隆抗体（PF06741086）增加了抑制剂血友病血浆中的止血，而不是过量凝血酶产生
3. Higher Concentrations of Heparin and Hirudin Are Required to Inhibit Thrombin Generation in Tissue Factor|[ndash]|Activated Cord Plasma Than in Adult Plasma [J] . Katrin Baier, Gerhard Cvirn, Peter Fritsch, Pediatric Research . 2005,第5aParta1期

机译：与成人血浆相比，需要更高浓度的肝素和水rud素抑制组织因子中凝血酶的产生
4. Effects of Tissue Factor Pathway Inhibitor and Antlthrombin on Thrombin Generation in Tissue Factor-actiwated Cord Plasma [C] . G. Cvirn, S. Gallistl, B. Leschnik, Hemophilie-Symposion . 2003

机译：组织因子途径抑制剂和抗细胞间抑制作用对组织因子致脊髓等离子体血栓形成的影响
5. Characterization of VLDL receptor interactions with plasma proteins lipoprotein(a), apolipoprotein E, tissue factor pathway inhibitor, and factor VIII [D] . Ruiz, Jose Fernando 2004

机译：VLDL受体与血浆蛋白脂蛋白（a），载脂蛋白E，组织因子途径抑制剂和因子VIII相互作用的表征
6. The effect of corn trypsin inhibitor, anti-tissue factor pathway inhibitor antibodies and phospholipids on microvesicle-associated thrombin generation in patients with pancreatic cancer and healthy controls [O] . Marit Hellum, Isabel Franco-Lie, Reidun Øvstebø, 2011

机译：玉米胰蛋白酶抑制剂，抗组织因子途径抑制剂抗体和磷脂对胰腺癌患者和健康对照组微囊相关凝血酶生成的影响
7. Higher Concentrations of Heparin and Hirudin Are Required to Inhibit Thrombin Generation in Tissue Factor–Activated Cord Plasma Than in Adult Plasma [O] . Katrin Baier, Gerhard Cvirn, Peter Fritsch, 2005

机译：需要较高浓度的肝素和血红素，以抑制组织因子活化帘子质等离子体中的凝血酶产生而不是成年等离子体

Effects of Tissue Factor Pathway Inhibitor and Antlthrombin on Thrombin Generation in Tissue Factor-actiwated Cord Plasma

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