Glucose Micro- and Nano-Sensors Based on Nanoassembled Enzyme/Polymer/Dye Composites

机译：基于纳米配合酶/聚合物/染料复合材料的葡萄糖微型和纳米传感器

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Minimally-invasive glucose sensors are attractive for disease management as well as medical and biological research applications. Fluorescent sensors, coupling enzymes to catalyze specific reactions with glucose, have been developed for this purpose. Our work has focused on the downscaling of these technologies to the micro- and nano-scale by using self-assembly to build the sensing components of the assays. Both "solid" polymers and hollow microshells have been developed to physically couple the sensing materials together in biocompatible, semipermeable packages suitable for use in biological systems. Fabrication details and sensor characterization are used to demonstrate the potential of these sensor concepts.

机译：微创葡萄糖传感器对疾病管理以及医学和生物学研究应用具有吸引力。为此目的，已经开发出荧光传感器，以催化与葡萄糖的特异性反应的偶联酶。我们的工作通过使用自组装来构建测定的传感组分，专注于微型和纳米级对微型和纳米级的缩小。已经开发了“固体”聚合物和中空微壳，以在适用于生物系统的生物相容的，半透封装中将传感材料与其一起进行一起。制造细节和传感器表征用于展示这些传感器概念的潜力。

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《Society of Photo-Optical Instrumentation Engineers Conference on Optical Diagnostics and Sensing》|2004年||共10页
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J. Quincy Brown; Suruchi Chopra; Patrick S. Grant; Michael J. McShane; SPIE-The International Society for Optical Engineering; SPIE v.5325 and Progress in Biomedical Optics and Imaging v.5 no.14;
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中图分类 N-532;
关键词
glucose sensing; biosensors; microspheres; nanoparticles; fluorescence; self-assembly; nanoassembly;

机译：葡萄糖感应;生物传感器;微球;纳米粒子;荧光;自组装;纳米组装;

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4. Glucose Micro- and Nano-Sensors Based on Nanoassembled Enzyme/Polymer/Dye Composites [C] . J. Quincy Brown, Suruchi Chopra, Patrick S. Grant, Conference on Optical Diagnostics and Sensing IV; 20040127; San Jose,CA; US . 2004

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6. Enzyme Immobilization Strategies and Electropolymerization Conditions to Control Sensitivity and Selectivity Parameters of a Polymer-Enzyme Composite Glucose Biosensor [O] . Sharon A. Rothwell, Sarah J. Killoran, Robert D. O’Neill 2010

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8. Structural Foaming at the Nano-, Micro-, and Macro-Scales of Continuous Carbon Fiber Reinforced Polymer Matrix Composites. [R] . J. C. Seferis 2012

机译：连续碳纤维增强聚合物基复合材料的纳米，微观和宏观尺度的结构发泡。

Glucose Micro- and Nano-Sensors Based on Nanoassembled Enzyme/Polymer/Dye Composites

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