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Osteoarthropathy in Patients with Neuropathic Pain

机译：神经性疼痛患者的骨质病病变

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Osteoarthropathy may follow lesions both in peripheral and central nervous systems. Altered bone metabolism by neurotransmitters released from affected sensory or sympathetic nerves may be involved in the pathogenesis of osteoarthropathy. Inflammatory cytokines have significant effects on RANK/RANKL/osteoprotegrin system. Thus those cytokines released from Schwann cells and infiltrated macrophages after nerve injury may play important roles in the pathogenesis of bony changes. Glucocorticosteroids seem to be useful for treating osteoarthropathy through suppressing production of those cytokines. Diagnosis and treatment of neuropathic osteoarthropathy are important for alleviation of both pain and suffering in patients with neuropathic pain if they have osteoarthropathy.

机译：骨关节病可能遵循外周和中枢神经系统的病变。受影响的感觉或交感神经中释放的神经递质的改变的骨代谢可能参与骨关节病的发病机制。炎症细胞因子对等级/ Rankl /骨蛋白系统具有显着影响。因此，那些在神经损伤后从Schwann细胞中释放的细胞因子和渗透巨噬细胞可能在骨骼变化的发病机制中起重要作用。通过抑制那些细胞因子的产生，糖皮质激素似乎可用于治疗骨球化病。神经病性骨质病的诊断和治疗对于缓解神经性疼痛患者的疼痛和痛苦是重要的。

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《International Pain Clinic》|2004年||共6页
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K. Moriwaki; O. Yuge;
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中图分类疼痛;
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1. Prevalence of Neuropathic Pain and Patient-Reported Outcomes in Korean Adults with Chronic Low Back Pain Resulting from Neuropathic Low Back Pain [J] . Kim Jin-Hwan, Hong Jae Taek, Lee Chong-Suh, Asian spine journal. . 2017,第6期

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2. Prevalence of Neuropathic Pain and Patient-Reported Outcomes in Korean Adults with Chronic Low Back Pain Resulting from Neuropathic Low Back Pain [J] . Kim Jin-Hwan, Hong Jae Taek, Lee Chong-Suh, Asian spine journal. . 2017,第6期

机译：神经性疼痛的发生率和患者报告的韩国成年人因神经性腰痛引起的慢性下背部疼痛
3. Prevalence of Neuropathic Pain among Patients with Chronic Low-Back Pain in the Arabian Gulf Region Assessed Using the Leeds Assessment of Neuropathic Symptoms and Signs Pain Scale [J] . W El Sissi, A Arnaout, MW Chaarani, Journal of International Medical Research . 2010,第6期

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4. Osteoarthropathy in Patients with Neuropathic Pain [C] . K. Moriwaki, O. Yuge International Pain Clinic . 2004

机译：神经性疼痛患者的骨质病病变
5. The role of N-acetyl-L-cysteine (NAC) as an adjuvant to opioid treatment in patients with inadequately controlled chronic neuropathic pain. [D] . Moore, Thomas Burton. 2016

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6. Prevalence of Neuropathic Pain and Patient-Reported Outcomes in Korean Adults with Chronic Low Back Pain Resulting from Neuropathic Low Back Pain [O] . Jin-Hwan Kim, Jae Taek Hong, Chong-Suh Lee, 2017

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Osteoarthropathy in Patients with Neuropathic Pain

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