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Modeling and Analyzing Biomedical Processes using Workflow/Petri Net Models and Tools

机译:使用工作流程/培养网模型和工具建模和分析生物医学过程

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Computer simulation enables system developers to execute a model of an actual or theoretical system on a computer and analyze the execution output. We have been exploring the use of Petri Net (PN) tools to study the behavior of systems that are represented using three kinds of biomedical models: a biological workflow model used to represent biological processes, and two different computer-interpretable models of health care processes that are derived from clinical guidelines. We developed and implemented software that maps the three models into a single underlying process model (workflow), which is then converted into PNs in formats that are readable by several PN simulation and analysis tools We show how these analysis tools enabled us to simulate and study the behavior of two biomedical systems: a Malaria parasite invading a host cell, and patients undergoing management of chronic cough.
机译:计算机模拟使系统开发人员能够在计算机上执行实际或理论系统的模型,并分析执行输出。我们一直在探索使用Petri网(PN)工具来研究使用三种生物医学模型表示的系统的行为:用于代表生物过程的生物工作流程模型,以及两种不同的医疗过程模型这是临床指南的。我们开发和实现了将三种模型映射到单个底层过程模型(工作流程)的软件,然后以几个PN仿真和分析工具可读的格式转换为PNS,我们展示了这些分析工具使我们能够模拟和研究。两种生物医学系统的行为:侵袭宿主细胞的疟疾寄生虫,以及接受慢性咳嗽的患者。

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