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The Combination of Inhibitors of Lymphocyte Activation Hydroxyurea (HU), Didox (DX), and Trimidox (TX)) in Combination with the Reverse Transcriptase Inhibitors (RTI): Abacavir (ABC), Didanosine (ddI), and Tenofovir (TFV) in the Murine Model of Immun

机译：淋巴细胞活化羟基脲（HU），牛（DX）和三苯并（TX）的抑制剂的组合与逆转录酶抑制剂（RTI）组合：ABACAVIR（ABC），脱氨酸（DDI）和替诺福韦（TFV） IMMUN的鼠模型

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Inhibiting cellular deoxynucleotide synthesis to is being evaluated to treat HIV infection based on the success of clinical trials in which the activity of the reverse transcriptase inhibitor (RTI) ddI was enhanced by the RR inhibitor HU. This report shows the ability of RRIs HU, TX, and DX to enhance the anti-viral activity of ABC, ddI, and TFV in-vivo.

机译：抑制细胞脱氧核苷酸合成待评估以基于临床试验的成功治疗HIV感染，其中RR抑制剂胡逆转录酶抑制剂（RTI）DDI的活性增强了逆转录酶抑制剂（RTI）DDI的活性。本报告显示RRIS HU，TX和DX能够增强ABC，DDI和TFV In-Vivo的抗病毒活性的能力。

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《International AIDS Conference》|2004年||共4页
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R. Sumpter; M. Inayat; C. Mayhew;
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中图分类获得性免疫缺陷综合征（AIDS艾滋病）;
关键词
Didanosine; HU; Combined; alcoholic beverage control board; Established diagnosis;

机译：脱蛋白;胡;合并;含酒精饮料控制板;既定诊断;

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1. Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease. [J] . Mayhew CN, Sumpter R, Inayat M, Antiviral Research . 2005,第1期

机译：淋巴细胞活化抑制剂（羟基脲，三聚体和二氧嘧啶）和逆转录酶（地丹宁）的组合可抑制鼠逆转录病毒诱导的淋巴增生性疾病的发展。
2. In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease. [J] . Sumpter LR, Inayat MS, Yost EE, Antiviral Research . 2004,第3期

机译：体内对羟基脲和新型核糖核苷酸还原酶抑制剂曲美多昔和双氧嘧啶与逆转录酶抑制剂阿巴卡韦的结合进行体内检查：抑制逆转录病毒引起的免疫缺陷病。
3. Short-term treatment with novel ribonucleotide reductase inhibitors Trimidox and Didox reverses late-stage murine retrovirus-induced lymphoproliferative disease with less bone marrow toxicity than hydroxyurea. [J] . Mayhew CN, Phillips JD, Cibull ML, Antiviral chemistry & chemotherapy . 2002,第5期

机译：新型核糖核苷酸还原酶抑制剂Trimidox和Didox的短期治疗可逆转晚期鼠逆转录病毒诱导的淋巴增生性疾病，其骨髓毒性比羟基脲少。
4. The Combination of Inhibitors of Lymphocyte Activation Hydroxyurea (HU), Didox (DX), and Trimidox (TX)) in Combination with the Reverse Transcriptase Inhibitors (RTI): Abacavir (ABC), Didanosine (ddI), and Tenofovir (TFV) in the Murine Model of Immun [C] . R. Sumpter, M. Inayat, C. Mayhew International AIDS Conference . 2004

机译：淋巴细胞活化羟基脲（HU），牛（DX）和三苯并（TX）的抑制剂的组合与逆转录酶抑制剂（RTI）组合：ABACAVIR（ABC），脱氨酸（DDI）和替诺福韦（TFV） IMMUN的鼠模型
5. Interactions between Buprenorphine and Antiretrovirals: Nucleos(t)ide Reverse Transcriptase Inhibitors (NRTI) Didanosine Lamivudine and Tenofovir [O] . Jennifer Baker, Petrie M. Rainey, David E. Moody, -1

机译：核苷（酸）IDE逆转录酶抑制剂（NRTI）去羟肌苷拉米夫定替诺福韦和：丁丙诺啡和抗逆转录病毒药物之间的相互作用
6. Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease. [O] . Mayhew Christopher N., Sumpter Ryan, Inayat Mohammed, 2005

机译：淋巴细胞活化抑制剂（羟基脲，三聚体和二氧嘧啶）和逆转录酶（地丹宁）的组合可抑制鼠逆转录病毒诱导的淋巴增生性疾病的发展。

The Combination of Inhibitors of Lymphocyte Activation Hydroxyurea (HU), Didox (DX), and Trimidox (TX)) in Combination with the Reverse Transcriptase Inhibitors (RTI): Abacavir (ABC), Didanosine (ddI), and Tenofovir (TFV) in the Murine Model of Immun

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