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Vasoactive Intestinal Peptide (VIP) Conjugated Phospholipid Nanocarrier for Active Targeted Delivery of Paclitaxel to Breast Cancer

机译：血管活性肠肽（VIP）缀合的磷脂纳米载体，用于紫杉醇至乳腺癌的活性靶向递送

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Paclitaxel, an efficacious anticancer drug, is not cancer cell-specific resulting in low therapeutic index. Receptors of vasoactive intestinal peptide (VIP) are overexpressed in breast cancer. The purpose of this study was to develop an active targeted phospholipid nanocarrier solubilizing paclitaxel for breast cancer using VIP as the targeting moiety and to determine its activity in vitro.

机译：Paclitaxel是一种有效的抗癌药物，不是癌细胞特异性，导致治疗指数低。血管活性肠肽（VIP）的受体在乳腺癌中过表达。本研究的目的是使用VIP作为靶向部分，开发一种活性靶向磷脂纳米载体溶解紫杉醇，用于靶向部分，并在体外测定其活性。

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《Controlled Release Society annual meeting》|2004年||共2页
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中图分类生物工程学（生物技术）;
关键词
drug targeting; phospholipid micelles; anticancer agents; paclitaxel;

机译：药物靶向;磷脂胶束;抗癌代理人;紫杉醇;

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专利

1. Folate receptor targeted delivery of paclitaxel to breast cancer cells via folic acid conjugated graphene oxide grafted methyl acrylate nanocarrier [J] . Vinothini Kandasamy, Rajendran Naresh Kumar, Ramu Andy, Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2019,第期

机译：叶酸受体通过叶酸共轭石墨烯氧化物接枝丙烯酸甲酯纳米载体靶向紫杉醇至乳腺癌细胞的递送至乳腺癌细胞
2. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) receptor specific peptide analogues for PET imaging of breast cancer: In vitro/in vivo evaluation. [J] . Zhang K, Aruva MR, Shanthly N, Regulatory peptides. . 2007,第1a3期

机译：用于乳腺癌PET成像的血管活性肠肽（VIP）和垂体腺苷酸环化酶激活肽（PACAP）受体特异性肽类似物：体外/体内评估。
3. Nuclear localization of vasoactive intestinal peptide (VIP) receptors in human breast cancer. [J] . Valdehita A, Bajo AM, Fernandez Martinez AB, Peptides: An International Journal . 2010,第11期

机译：人乳腺癌中血管活性肠肽（VIP）受体的核定位。
4. Vasoactive Intestinal Peptide (VIP) Conjugated Phospholipid Nanocarrier for Active Targeted Delivery of Paclitaxel to Breast Cancer [C] . Controlled Release Society annual meeting . 2004

机译：血管活性肠肽（VIP）缀合的磷脂纳米载体，用于紫杉醇至乳腺癌的活性靶向递送
5. Development and Characterization of LDV Peptide Targeted Nanocarriers for Paclitaxel Delivery: A Comparative Study of Micelles, Liposomes and Solid Lipid Nanoparticles [D] . Dattani, Poonam. 2019

机译：紫杉醇传递的LDV肽靶向纳米载体的开发和表征：胶束，脂质体和固体脂质纳米颗粒的比较研究。
6. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) receptor specific peptide analogues for PET imaging of breast cancer: Invitro/invivo evaluation [O] . Dr. Kaijun Zhang, Dr. Mohan R. Aruva, Dr. Nylla Shanthly, -1

机译：用于乳腺癌PET成像的血管活性肠肽（VIP）和垂体腺苷酸环化酶激活肽（PACAP）受体特异性肽类似物：体外/体内评估
7. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) receptor specific peptide analogues for PET imaging of breast cancer: In vitro/in vivo evaluation [O] . Kaijun Zhang, Mohan R. Aruva, Nylla Shanthly, 2007

机译：血管活性肠肽（VIP）和垂体腺苷酸环酶活化肽（PACAP）受体特异性肽类似物用于乳腺癌的PET成像：体外/体内评价

Vasoactive Intestinal Peptide (VIP) Conjugated Phospholipid Nanocarrier for Active Targeted Delivery of Paclitaxel to Breast Cancer

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