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An assessment of working memory using P300 wave in healthy subjects

机译：在健康主题中使用P300波进行工作记忆的评估

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Working memory (WM) has three cognitive components, i.e. encoding and retaining of information, and the retrieval of stored expressions. It is accepted that the left frontal slow wave negativity is an indicator of the functions of working memory. This study aims to investigate the encoded functions of working memory through the variations in the amplitude and latency of P300 wave recorded from three separate locations (Fz, Cz and Pz). The study was performed on five healthy subjects with ages varying between 25 and 30 in the Institute of Cognitive Sciences of Bremen University. The task given to the subjects was to define the stimuli by pressing the buttons in their right and left hands. Event-related potentials (ERPs) were elicited from increasing working memory load in three conditions of an n-back task. It was observed that the amplitude of P300 was low in Fz when compared with those in Cz and Pz. Meaningfully significant differences of P300 amplitude were found among locations only in two-back task (Fz: 5.32+4.93, Cz: 6.55+-5.31, Pz: 9.97+-6.19; p<0.05). There were no differences for P300 latency in Fz, Pz and Cz locations. It was concluded that P300 amplitude increased in parallel with the increase in load of working memory.
机译：工作存储器（WM）具有三个认知成分，即编码和保持的信息，并存储表达式的检索。它被接受的是，左额叶慢波消极是工作记忆的功能的指示器。本研究旨在通过在振幅变化调查工作存储器的编码功能和延迟P300波从三个不同的位置（Fz的，CZ和PZ）记录。这项研究是年龄在不来梅大学认知科学研究所25和30之间变化的五个健康受试者进行。给予受试者的任务是按他们的右手和左手的按钮来定义刺激。事件相关电位（ERP）是从在n-back任务的三个条件，提高工作记忆负荷引起的。据观察，当与那些在锆石及的Pz相比P300的振幅在Fz的低。 P300振幅的有意义显著差异仅在两回任务地点之间被发现（Fz的：5.32 + 4.93，CZ：6.55 + -5.31，的Pz：9.97 + -6.19; P <0.05）。有在Fz的，的Pz及锆位置P300潜伏期无显着差异。得出的结论是P300振幅平行于工作存储器的负荷的增加而增加。

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