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Plasticity in the descending motor pathways after spinal cord hemisection

机译:脊髓半切割后下降电动机途径的可塑性

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The present study evaluates the motor functional recovery after C2 spinal cord hemisection combined with contralateral brachial root tcansection, which causes a condition that is similar to the crossed phrenic phenomenon (CPP). Descending motor pathways, including the reticulospinal extrapyramidal tract and corticospinal pyramidal tracts, were evaluated by transcranial magnetic motor-evoked potentials (mMEPs) and direct cortical electrical motor-evoked potentials (eMEP), respectively. All MEPs recorded from the left forelimb were abolished immediately after the left C2 hemisection. Left mMEPs recovered dramatically immediately after contralateral right brachial root transection. Corticospinal eMEPs never recovered, regardless of transection. The facilitation of mMEPs in animals that had undergone combined contralateral root transection was well correlated with open-field behavioral motor performance.
机译:本研究评估C2脊髓半切割后的电动机功能恢复与对侧肱骨根TCancection联系,这导致伴有与交叉的膈现象(CPP)相似的病症。通过经颅磁电动机诱发电位(MMEPS)和直接皮质电动电动电动机诱发电位(EMEP)评估包括近序旋转瘤瘤沟和皮质脊髓锥体的电动机途径。在左C2半切断后立即被留下的所有MEPS被废除。在对侧右肱骨根转段后立即急于立即恢复MMEP。无论转化如何,皮质统计学EMEP都从未恢复过。在经过组合对侧根横截面的动物中的促进与开放场行为电机性能很好。

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