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首页> 外文会议>International Congress on Sound and Vibration >NEUROLOGICAL DISORDERS IN VIBROACOUSTIC DISEASE III - RESPIRATORY CONTROL
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NEUROLOGICAL DISORDERS IN VIBROACOUSTIC DISEASE III - RESPIRATORY CONTROL

机译：蛛旋疾病中的神经障碍III - 呼吸控制

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Introduction. Central nervous system disorders in workers exposed to low frequency noise (LFN, <500 Hz, including infrasound) were first observed 25 years ago, among aircraft technicians. Concurrently, respiratory pathology was identified in these workers, and later reproduced in LFN-exposed animal models. Today, vibroacoustic disease (VAD) is defined as the systemic pathology caused by excessive exposure to LFN. The respiratory tract continues to be under heavy scrutiny in both LFN-exposed humans and animal models, and has been confirmed as a major target for LFN-induced damage. Given that both the respiratory and central nervous systems were both compromised in these workers, it became pertinent to investigate the status of the neurological control of breathing in VAD patients. Methods. The P{sub}0.1 value, a measure of the suction pressure developed at the mouth 0.1 seconds after the start of inspiration, depends on the respiratory centres and the autonomic nervous system pathway of the neural control of respiratory function. By rebreathing CO{sub}2, (6% in air) normal individuals present an average seven-fold increase in P{sub} 0.1(CO{sub}2) as compared to basal P0.1. Twenty-two male VAD patients underwent the P{sub} 0.1(CO{sub}2) index respiratory drive tests, as well as standard pulmonary function tests. Results. Pulmonary function tests were normal in both VAD patients and controls. The P{sub}0.1(CO{sub}2) index was below average value in VAD patients (average: 22.9%) while it presented normal values in the control group (average >60%). Discussion. The neurological control of breathing is compromised in VAD patients.
机译：介绍。在25年前，首次在飞机技术人员中首次观察到暴露于低频噪声（LFN，<500 Hz，包括脱机）的工人的中枢神经系统障碍。同时，在这些工人中发现了呼吸道理，后来在LFN暴露的动物模型中繁殖。如今，蛛座声学疾病（VAD）被定义为由过度暴露于LFN引起的全身病理学。呼吸道在LFN暴露的人类和动物模型中继续受到严重审查，并且已被证实为LFN诱导损伤的主要目标。鉴于呼吸系统和中枢神经系统都遭到损害，探讨了VAD患者呼吸神经控制的状态。方法。 P {亚} 0.1值，衡量灵感后口口0.1秒的吸入压力，取决于呼吸中心和神经控制的神经控制呼吸功能。通过再呼吸CO {子} 2，（在空气中6％）正常个体存在于p {子}的平均增长7倍0.1（CO {子} 2）相比基底P0.1为。二十二个雄性VAD患者接受了P {次} 0.1（CO {次} 2）指数呼​​吸驱动试验，以及标准的肺功能测试。结果。 VAD患者和对照中的肺功能测试是正常的。 P {亚} 0.1（CO {Sub} 2）指数低于VAD患者的平均值（平均：22.9％），而在对照组中呈现正常值（平均> 60％）。讨论。 VAD患者呼吸的神经系统控制受损。

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