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Solubility of Sodium L- Ascorbate in the Methanol Aqueous Solution and Ethanol Aqueous Solution and Its Application for purification and Crystallization of Sodium L-Ascorbate

机译:L-抗坏血酸钠在甲醇水溶液和乙醇水溶液中的溶解度及其纯化和结晶L-抗坏血酸钠的应用

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Sodium L-ascorbate (C6H7NaO6, CAS registry No. 134-03-2, Fig. 1) is one of a number of mineral salts of ascorbic acid (vitamin C). [1] The human body does not produce its own vitamin C; it gets it from food and other sources. Ascorbic acid is highly reactive, and the most powerful and fastest acting form of vitamin C. However, it is too acidic to safely use intravenously. While ascorbic acid is more powerful fighting infections and perhaps even heart disease, some people find as the age that ascorbic acid becomes harder to take by mouth. Cells in the stomach are used to a highly acidic environment, but sometimes lesions form at the bottom of the esophagus, as tissues leading to the stomach are not acid protected. For people who are experiencing discomfort while swallowing, and are not fighting the cold or the flu, sodium ascorbate powder can be an excellent choice. Moreover, the degradation of Ascorbic acid is inevitable. [2-4] As a form of vitamin C, the basic properties and health benefits of sodium ascorbate are virtually identical with ascorbic acid, but the mineral salt buffers, thus lowers the acidity of ascorbic acid. [5] The buffered sodium ascorbate may enter the blood stream more slowly than ascorbic acid when taken orally. Sodium ascorbate is used for intravenous infusions, intramuscular injections, and is used orally to avoid the acidity of ascorbic acid by sensitive persons. Moreover, as a food additive, it has the E number E301 and used as antioxidant and an acidity regulator. It is approved for use as a food additive in the EU, USA, Australia and New Zealand. [6-8]
机译:L-抗坏血酸钠(C6H7NAO6,CAS注册表No.34-03-2,图1)是抗坏血酸(维生素C)的多种矿物盐之一。 [1]人体不会产生自己的维生素C;它从食物和其他来源得到它。抗坏血酸是高反应性的,以及最强大且最快的维生素C形式。然而,它太酸性地静脉安全使用。虽然抗坏血酸更强大的战斗感染和甚至心脏病,但有些人发现抗坏血酸变得越来越难以口服。胃中的细胞用于高度酸性环境,但有时在食道底部的病变形式,因为导致胃的组织不受酸受保护。对于在吞咽时经历不适的人,并且没有对抗感冒或流感,抗坏血酸钠可以是一个绝佳的选择。此外,抗坏血酸的降解是不可避免的。 [2-4]作为维生素C的形式,抗坏血酸钠的基本性质和健康益处几乎与抗坏血酸相同,但矿物盐缓冲液,从而降低了抗坏血酸的酸度。 [5]缓冲的抗坏血酸钠可以在口服时比抗坏血酸更慢地进入血液流。抗坏血酸钠用于静脉内输注,肌内注射,并用敏感人口服使用以避免抗坏血酸的酸度。此外,作为食品添加剂,它具有E号E301并用作抗氧化剂和酸度调节剂。它被批准用于欧盟,美国,澳大利亚和新西兰的食品添加剂。 [6-8]

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