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PHOTORECEPTION FOR THE NEUROBEHAVIORAL EFFECTS OF LIGHT IN HUMANS

机译:用于人类光的神经衰弱作用的感光

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Four traditional objectives of architecturallighting have been to provide light that: 1) is optimum for visual performance; 2) is visually comfortable; 3) permits aesthetic appreciation of the space; and 4) conserves energy [1-2]. During the past three decades, scientific evidence has led to a growing appreciation that, relatively separate from vision and visual reflexes, light perceived by the eye can be a potent biological, behavioral, and therapeutic stimulus in humans [3-7]. Recently, there has been an upheaval in the understanding of photoreceptive input to the circadian and neuroendocrine systems of humans and other mammalian species. A study on healthy human subjects confirmed that the three-cone system that mediates human photopic vision is not the primary photoreceptor system that transduces light stimuli for acute melatonin suppression [8]. This discovery was rapidly followed by the elucidation of two action spectra in healthy human subjects that identified 446-477 nm as the most potent wavelength region for melatonin suppression [9,10]. Those data suggested that a novel photosensory system, distinct from the visual rods and cones, is primarily responsible for regulating melatonin in humans.
机译:建筑的四个传统目标已经提供了光明:1)对于视觉性能而言是最佳的; 2)视觉舒适; 3)允许对空间的审美欣赏; 4)保存能量[1-2]。在过去的三十年中,科学证据导致了越来越欣赏,从视觉和视觉反射中相对分离,眼睛感知的光可以是人类的有效的生物学,行为和治疗刺激[3-7]。最近,对人类和其他哺乳动物物种的昼夜野生病和神经内分泌系统的光敏投入进行了动荡。对健康人类受试者的研究证实,介导人光学视觉的三锥形系统不是转换急性褪黑素抑制的光刺激的主要感光体系[8]。这种发现迅速,然后阐明了在健康的人体受试者中阐明了鉴定了446-477nm作为褪黑素抑制的最有效波长区域[9,10]。这些数据表明,一种新的光敏系统,与视觉杆和锥体不同,主要负责调节人类的褪黑激素。

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