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Photoacoustic and Thermoacoustic Tomography with both Optical and Electrical Contrasts

机译:光声和热声学断层扫描,具有光学和电气对比

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The absorption of electromagnetic energy causes thermal expansion and induces acoustic waves in biological tissues. Various tissues present particular characteristics in their absorption spectra. To acquire both photoacoustic and thermoacoustic images with multiple contrasts that reflect the absorption of electromagnetic energy, biological tissues are stimulated using laser and microwave pulses, respectively. Muscles with a rich blood supply strongly absorb green optical radiation, which provides excellent optical contrast. High water content tissues, such as connective tissue and muscle tissue, display high contrast to fatty tissues when imaged using microwave radiation. Most cancerous tissues have higher water and ionic concentrations, two characteristics that are also associated with angiogenesis and hemoglobin oxygen saturation. Therefore, cancer diagnosis based on information from tissue properties over an electromagnetic spectrum from microwave to optical bands can be more accurate than was previously available.
机译:电磁能量的吸收导致热膨胀并在生物组织中引起声波。各种组织在吸收光谱中呈现特定特征。为了在具有反映电磁能吸收的多个对比度的光声和热声图像,分别使用激光和微波脉冲刺激生物组织。富有血液供应的肌肉强烈吸收绿色光学辐射,提供出色的光学对比度。高水含量组织,如结缔组织和肌肉组织,在使用微波辐射成像时显示与脂肪组织的高对比度。大多数癌组织具有较高的水和离子浓度,两种特征也与血管生成和血红蛋白氧饱和相同。因此,基于从微波到光带的电磁谱的组织特性信息的癌症诊断可以比以前可用的更准确。

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