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Anatomopathology of paratuberculosis in dairy cattle from Rio de Janeiro, Brazil

机译：巴西里约热内卢奶牛牛皮坪的解剖学病理学

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The purpose of this study was to describe the anatomopathological findings of three cases of paratuberculosis in autochthonous dairy cattle from Rio de Janeiro, Brazil. Animals presented characteristic clinical symptoms of paratuberculosis as cachexia, diarrhea and leanness, and were first diagnosed by sero-reactivity to an in-house ELISA. Animals were sacrificed and samples of small and large intestines, mesenteric lymph nodes and ileocaecal valve were collected and processed for both histopathology and bacteriology. Tissues were fixed in 10% buffered formalin, processed for paraffin inclusion and stained by both HE (haemathoxilin-eosin) and ZN (Ziehl-Neelsen) methods. Macroscopic alterations such as small intestine wall segmental thickness, mucosal hyperaemia and prominent corrugation were observed; ileocaecal valve emaciation, evident mesenteric lymphadenomegally, and lymphangiectasis were also noted. The main histopathological findings were enteritis, lymphangitis and granulomatous lymphadenitis.
机译：本研究的目的是描述来自巴西里约热内卢的自动紧张乳制品牛皮病患者的解剖病理学发现。动物呈现了副植物，腹泻和瘦的特征临床症状，并首先被血清反应性诊断到内部ELISA。处死动物，并收集小和大肠的样品，肠系膜淋巴结和对联瓣膜，用于组织病理学和细菌学。将组织固定在10％缓冲的福尔马林中，处理用于石蜡包裹物并通过他（Haemathoxilin-eosin）和Zn（Ziehl-Neelsen）方法染色。宏观改变如小肠壁节段厚度，粘膜高血肿和突出的波纹等;还注意到了对象瓣膜裂缝，显而易见的肠系膜淋巴结，和淋巴噬炎。主要的组织病理学发现是肠炎，淋巴炎和肉芽肿性淋巴腺炎。

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