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Epidemiological Aspects of Canine Visceral Leishmaniosis in Azarshahr a New Endemic Focus of Kala-Azar in the Islamic Republic of Iran

机译:Azarshahr犬内脏Leishmaniosis的流行病学方面在伊朗伊斯兰共和国Kala-Azar新的地方性重点

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An epidemiological study to examine the sero-prevalence of zoonotic visceral leishmaniosis (ZVL) among domestic and wild canines in endemic foci of Azarshahr county of Iran was carried out during 2004-2005 to assess the distribution of the disease and the possible association between infection in dogs, wild canines and people. Anti-leishmanial antibodies were detected by the direct agglutination test (DAT). Parasitological study was performed for all captured wild canines and were detected in some of the seropositive dogs with specific clinical signs (n = 120). Serum samples (n=1568) were collected from domestic dogs in villages that are known endemic foci of human visceral leishmaniosis (HVL). Wild canine sera were collected from jackals {Cards aureus, n = 10), foxes (Vulpes vulpes, n = 10) and wolves {Cards lupus, n= 10). Of the 120 serum sampled collected from domestic dogs, 23(19.7%)were positive by DAT (1:320 and above) and IFAT (1:160 and above).40(33.3%) of the dogs had lower liters than positive titer. No statistically significant difference was found between male and female sero-prevalence (P = 0.083). Dogs of 8 years and above showed the highest sero-prevalence (40.6%). Only 23.9% of the seropositive domestic dogs had clinical signs. Parasitology and serology tests that were performed in 30 wild canines showed 10% these animals were infected by Leishmania infantum. Fifteen of Leishmania spp. isolated from the dogs and wild canines were identified as Leishmania infantum by molecular techniques.
机译:流行病学研究,探讨伊朗Azarshahr县的地方性疫源家养和野生犬类进行之中人畜共患内脏利什曼病(ZVL)的血清阳性率在2004-2005年期间,以评估疾病的分布和感染的可能的关联狗,野生犬科动物和人。抗利什曼病抗体的直接凝集试验(DAT)检测。所有捕获的野生犬科动物进行寄生虫学研究中的一些阳性犬特定的临床症状(N = 120)的检测。血清样品(N = 1568),从国内的狗在已知的人类内脏利什曼病(HVL)的流行灶村收集。野生犬血清从豺{卡黄色葡萄球菌收集,N = 10),狐狸(赤狐,N = 10)和狼{卡狼疮,N = 10)。的120血清采样从家犬收集的,23(19.7%)为阳性通过DAT(1:320以上)和IFAT(1:160以上)0.40(33.3%)的狗的具有较低的升比阳性滴度。无统​​计学显著差异男性和女性血清阳性率(P = 0.083)之间找到。 8岁及以上的狗表现出最高的血清阳性率(40.6%)。只有23.9%的血清阳性家犬有临床症状。在30只野生犬科动物所执行的寄生虫学和血清学试验表明10%,这些动物是由利什曼原虫感染的婴儿。利什曼原虫的十五。从狗隔离和野生犬被认定为通过分子技术婴儿利什曼原虫。

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