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首页> 外文会议>Conference on Computers in Cardiology >Development of a Method for Determining Arterial Pulse Propagation Times and Influence of Arterial Compliance
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Development of a Method for Determining Arterial Pulse Propagation Times and Influence of Arterial Compliance

机译：一种确定动脉脉冲传播时间和动脉顺应性影响的方法

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The characteristics of the arterial wall play an important role in cardiovascular physiology and pathophysiology. Arteries are normally elastic or compliant, allowing the artery diameter to expand under pressure. However, very little is known about this important property, as it is difficult to assess in vivo. This study examined this property indirectly from measurements of the time the pulse took to radiate from the heart to peripheral sites on the body. By examining beat-to-beat changes in pulse timing, the effects on arterial compliance were estimated. Subjects with frequent ectopic beats were studied. Electrocardiogram (ECG) and finger and ear photoplethysmograph (PPG) recordings were obtained from all subjects. ECG-pulse times for ear and finger pulses were determined by computer algorithms. The differences in pulse propagation time between sinus beats and ectopic beats with lower pulse pressure were quantified. The ECG-pulse time for ectopic beats was significantly greater than for the sinus beats. The finger ECG-pulse time for ectopic beats was 344±14 ms compared with 228±11 ms for sinus beats (P<0.001), and the ear ECG-pulse time was 288±20 ms compared with 180±13 ms (P<0.001). The differences between the finger and ear ECG-pulse times allowed the pulse propagation time along the arm to be estimated. It was significantly longer for the ectopic beats than for the sinus beats (55.7±8.0 ms compared to 47.7±4.0 ms). This 18% change resulted from the lower pulse pressure of ectopic beats and increased arterial compliance of 42%.
机译：动脉壁的特征在心血管生理学和病理生理学中起重要作用。动脉通常是弹性或柔顺的，使动脉直径在压力下膨胀。然而，很少有关于这一重要性的重要性，因为难以在体内评估。本研究通过测量脉冲从心脏辐射到身体上的外周位点的测量来检查该性质。通过检查脉冲时序的节拍变化，估计了对动脉顺应性的影响。研究了具有频繁异位节拍的受试者。所有受试者都可以获得心电图（ECG）和手指和耳光电压仪（PPG）记录。通过计算机算法确定耳朵和手指脉冲的ECG脉冲次数。量化鼻窦搏动与具有较低脉冲压力的异位节拍之间的脉冲传播时间的差异。异位搏动的ECG脉冲时间明显大于窦搏。与窦搏动的228±11 ms相比，异位搏动的手指ECG脉冲时间为344±14毫秒（P <0.001），与180±13 ms相比，耳朵ECG脉冲时间为288±20 ms（P < 0.001）。手指和耳朵ECG脉冲时间之间的差异允许估计臂的脉冲传播时间。这是显著更长的异位搏动比用于窦性搏动（55.7±8.0毫秒相比47.7±4.0毫秒）。这18％的变化是由于异位节拍的较低脉冲压力导致，增加动脉顺应性为42％。

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