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首页> 外文会议>ASMS Conference on Mass Spectrometry and Allied Topics >Desorption Electrospray Ionization (DESI) - Direct Ionization under Ambient Pressures and Temperatures
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Desorption Electrospray Ionization (DESI) - Direct Ionization under Ambient Pressures and Temperatures

机译：解吸电喷雾电离（DESI） - 环境压力下的直接电离和温度

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Development of desorption electrospray ionization1 (DESI) has opened up a new area in the field known as "Ambient mass spectrometry~2". Development of DESI was followed by the development of a handful of new ionization methods having one common feature: none of them requires any preparation of condensed phase samples prior to analysis. DESI is differentiated by the fact that it is applicable to large as well as small molecules. The method also allows high throughput analysis and this makes it highly suited to applications to metabolomics and other demanding biological samples. Further unique applications include both in-vivo and ex-vivo mass spectrometric investigations of biological tissues. This presentation discusses DESI in the context of the related ambient ionization methods, especially desorption atmospheric pressure ionization(DAPCI) and direct analysis in real time5 (DART). We also introduce a new method of this general type, Jet Desorption Ionization (JeDI),which employs a high velocity, electrically charged water jet for desorption.
机译：解吸电喷雾离子化1（DESI）的开发在称为“环境质谱〜2”的田地中打开了一个新区域。随后的开发Desi的开发具有具有一个共同特征的少量新的电离方法：均未在分析之前需要任何制备浓缩相样品。 Desi因其适用于大以及小分子而有所不同。该方法还允许高通量分析，这使得这使得对代谢组学和其他要求苛刻的生物样品非常适合应用。进一步的独特应用包括生物组织的体内和前体内质谱研究。该介绍在相关的环境电离方法的背景下讨论Desi，特别是解吸大气压电离（DAPCI）和实时地的直接分析（DART）。我们还介绍了这种通用类型的新方法，喷射解吸电离（JEDI），其采用高速，电荷的水射流进行解吸。

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