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Direct Reaction Monitoring of Dis-infection By-product Formation using Membrane Introduction Mass Spectrometry

机译:使用膜引入质谱法直接反应监测DIS感染副产物的形成

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MIMS techniques provide quantitative information via introduction of analyte from a sample matrix into an ion-trap mass spectrometer through a semi-permeable membrane and have been successfully applied to environmental and reaction monitoring. Advantages include direct sample introduction, real-time capability and high sensitivity, particularly for volatile and semi-volatile analytes (VOC/SVOCs). We have employed this technique for monitoring the real-time formation kinetics of haloforms and haloacetonitriles during the chlorination of model compounds and natural surface waters. We have also used MIMS as a rapid screening tool to quantify initial formation rates of DBPs from several novel precursors including pharmaceuticals and anti-microbial agents present in complex aqueous mixtures.
机译:MIMS技术通过将分析物从样品基质引入离子阱质谱仪通过半透膜来提供定量信息,并且已成功地应用于环境和反应监测。优点包括直接样品引入,实时能力和高灵敏度,特别是对于挥发性和半挥发性分析物(VOC / SVOC)。在模型化合物和天然表面水的氯化过程中,我们采用了该技术监测HaloForms和Haloacetonitriles的实时形成动力学。我们还使用MIMS作为快速筛选工具,从包括在复合物水性混合物中存在的药物和抗微生物剂的几种新型前体来量化DBP的初始形成率。

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