Optimization of Parameters for Performing Electron Transfer Dissociation on 2D Linear Ion Traps

机译：对2D线性离子陷阱进行电子传递解离参数的优化

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Electron transfer dissociation has been demonstrated to be an extremely powerful dissociation technique for characterization of large multiply charged peptide and proteins1. This allows the performance of electron capture dissociation, traditionally done only on ICR instruments, to be achieved on RF quadrupole ion trap devices. In implementing the ETD technique, there are many parameters which must be considered in order to optimize its performance and produce useful data. These parameters include those associated with forming the reagent ions, storing the reagent and analyte ions simultaneously, and the ion-ion reaction conditions. These studies help to characterize and optimize many of these parameters.

机译：已经证明了电子转移解离是一种极其强大的解离技术，用于表征大型繁殖肽和蛋白质1。这允许电子捕获解离的性能，传统上仅在ICR仪器上完成，以实现RF四极杆子离子阱装置。在实现ETD技术时，存在许多必须考虑的参数，以便优化其性能并产生有用的数据。这些参数包括与形成试剂离子相关的那些，同时储存试剂和分析物离子和离子离子反应条件。这些研究有助于表征和优化许多这些参数。

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《ASMS Conference on Mass Spectrometry and Allied Topics》|2006年||共2页
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Jae C. Schwartz; Zhiqi Hao; Andreas Huhmer; John E. P. Syka; Josh Coon;
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中图分类 TB994.5-53;
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1. On Performing Simultaneous Electron Transfer Dissociation and Collision-Induced Dissociation on Multiply Protonated Peptides in a Linear Ion Trap [J] . Campbell JL, Hager JW, Le Blanc JCY Journal of the American Society for Mass Spectrometry . 2009,第9期

机译：关于在线性离子阱中对质子化的多肽同时进行电子转移解离和碰撞诱导解离
2. Ultrasensitive Characterization of Site-Specific Glycosylation of Affinity-Purified Haptoglobin from Lung Cancer Patient Plasma Using 10 μm i.d. Porous Layer Open Tubular Liquid Chromatography−Linear Ion Trap Collision-Induced Dissociation/Electron Transfer Dissociation Mass Spectrometry [J] . Dongdong Wang Marina Hincapie Tomas Rejtar and Barry L. Karger Analytical Chemistry . 2011,第6期

机译：使用10μmi.d.从肺癌患者血浆中亲和纯化的单珠蛋白的位点特异性糖基化的超灵敏表征多孔层开放管液相色谱-线性离子阱碰撞诱导解离/电子转移解离质谱
3. Implementation of Electron-Transfer Dissociation on a Hybrid Linear Ion Trap-Orbitrap Mass Spectrometer [J] . Graeme C. McAlister, Doug Phanstiel, David M. Good, Analytical chemistry . 2007,第10期

机译：混合线性离子阱-轨道阱质谱仪上电子转移解离的实现
4. Optimization of Parameters for Performing Electron Transfer Dissociation on 2D Linear Ion Traps [C] . Jae C. Schwartz, Zhiqi Hao, Andreas Huhmer, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：对2D线性离子陷阱进行电子传递解离参数的优化
5. Electron Transfer Dissociation and Collision-Induced Dissociation Mass Spectrometry of Metallated Oligosaccharides [D] . Schaller-Duke, Ranelle Marie. 2019

机译：金属转移解离和碰撞诱导的金属寡糖的解离质谱法
6. Implementation of Activated Ion Electron Transfer Dissociation on a quadrupole-Orbitrap-linear ion trap hybrid mass spectrometer [O] . Nicholas M. Riley, Michael S. Westphall, Alexander S. Hebert, -1

机译：四极杆-轨道阱-线性离子阱混合质谱仪上活化离子转移解离的实现
7. On Performing Simultaneous Electron Transfer Dissociation and Collision-Induced Dissociation on Multiply Protonated Peptides in a Linear Ion Trap [O] . Campbell J. Larry, Hager James W., Le Blanc J.C. Yves 2009

机译：关于在线性离子阱中对质子化的多肽同时进行电子转移解离和碰撞诱导解离

Optimization of Parameters for Performing Electron Transfer Dissociation on 2D Linear Ion Traps

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