首页> 外文会议>ASMS Conference on Mass Spectrometry and Allied Topics >Complete Trimethylation of Histone Lysine Residues and its Application to the Quantitation of Lysine Methylation Using Mass Spectrometry

【24h】

Complete Trimethylation of Histone Lysine Residues and its Application to the Quantitation of Lysine Methylation Using Mass Spectrometry

机译：通过质谱法将组蛋白赖氨酸残基的完全三甲基化及其应用于赖氨酸甲基化定量

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

Complete dimethylation of the lysines in histone H3 incorporating stable isotope labels was achieved. 12 of the 13 lysine residues in H3 were covered. Most of these lysines play important roles in cellular processes and may be potential biomarkers for disease progression and prevalence.

机译：达到了包含稳定同位素标记的组蛋白H3中赖氨酸的完全二甲基化。 H3中的13个赖氨酸残基的12个被覆盖。大多数这些赖氨酸在细胞过程中起重要作用，并且可能是疾病进展和患病率的潜在生物标志物。

著录项

来源
《ASMS Conference on Mass Spectrometry and Allied Topics》|2014年||共1页
会议地点
作者
Steven Toth; Anthony Berardinelli; Wendell P. Griffith;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类 TB994.5-53;
关键词

相似文献

外文文献
中文文献
专利

1. Histone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell Carcinoma [J] . Yu Qinqin, Liu Yanqing, Zheng Xiaoli, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2017,第1期

机译：组蛋白H3赖氨酸4三甲基化，赖氨酸27三甲基化和赖氨酸27乙酰化有助于肾细胞癌中溶质载体家族47成员2的转录抑制
2. Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. [J] . Binda O, LeRoy G, Bua DJ, Epigenetics: official journal of the DNA Methylation Society . 2010,第8期

机译：组蛋白H3赖氨酸4的三甲基化会损害组蛋白H3赖氨酸9的甲基化：赖氨酸甲基转移酶通过与底物的物理相互作用进行调节。
3. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys(27)) Trimethylation in Melanoma [J] . Sengupta Deepanwita, Byrum Stephanie D., Avaritt Nathan L., Molecular & cellular proteomics: MCP . 2016,第3期

机译：定量组蛋白质谱鉴定黑素瘤中组蛋白H3赖氨酸27（Lys（27））三甲基化水平升高
4. Complete Trimethylation of Histone Lysine Residues and its Application to the Quantitation of Lysine Methylation Using Mass Spectrometry [C] . Steven Toth, Anthony Berardinelli, Wendell P. Griffith ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：通过质谱法将组蛋白赖氨酸残基的完全三甲基化及其应用于赖氨酸甲基化定量
5. Complete Trimethylation of Lysine Residues and its Application to the Quantitation of Lysine Methylation in Histones using Mass Spectrometry. [D] . Toth, Steven. 2015

机译：赖氨酸残基的完全三甲基化及其在质谱分析组蛋白中赖氨酸甲基化中的应用。
6. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma [O] . Deepanwita Sengupta, Stephanie D. Byrum, Nathan L. Avaritt, 2016

机译：定量组蛋白质谱鉴定黑素瘤中组蛋白H3赖氨酸27（Lys27）三甲基化水平升高
7. Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: Regulation of lysine methyltransferases by physical interaction with their substrates [O] . Binda, Olivier, LeRoy, Gary, Bua, Dennis J, 2010

机译：组蛋白H3赖氨酸的三甲基化会损害组蛋白H3赖氨酸的甲基化9：赖氨酸甲基转移酶通过与底物的物理相互作用来调节

Complete Trimethylation of Histone Lysine Residues and its Application to the Quantitation of Lysine Methylation Using Mass Spectrometry

摘要

著录项

相似文献

相关主题

期刊订阅